Automated Workflow Offers PCR-Based Molecular Diagnostic Assay Menu

A novel, integrated system sets new standards for molecular testing and incorporates all workflow steps from sample to detection.

The system offers features that create flexibility, such as continuous loading, random access, open channels for user-developed tests, and a very broad menu of commercial assays. It has the ability to process an almost unlimited range of sample types and it should transform the laboratory's work in the emerging field of molecular diagnostic


This new and complete workflow solution is comprised of modules that can be used as standalone systems or combined into a fully integrated system. Called QIAsymphony RGQ, and introduced by Qiagen (Frankfurt, Germany), the system comprises the physical and data integration of the modules QIAsymphony SP for sample preparation, QIAsymphony AS for assay setup, and the Rotor-Gene Q real time polymerase chain reaction (PCR) thermocycler.

QIAsymphony provides the broadest available PCR-based assay menu, including the Artus real time PCR kits for the detection of human immunosuppression virus (HIV), Human hepatitis C and B viruses (HCV, HBV), and a transplantation panel with Cytomegalovirus (CMV), Epstein Bar virus (EBV), Herpes simplex virus (HSV), Varicella-Zoster (VZV) and BK virus (BKV1). (BK was the initials of the patient from whom the virus was first isolated).

A large pipeline of more tests will be launched in the coming months, including TheraScreen, epidermal growth factor receptor (EGFR), KRAS, as well as Artus Influenza, Computed tomography (CT), CT Neisseria gonorrhoeae (CT/Ng) and an extended transplantation panel. Many more tests are in development including integration of detection options such as pyrosequencing and multiplexing solutions.

Qiagen N.V., a Netherlands holding company, is a global provider of sample and assay technologies. Sample technologies are used to isolate and process DNA, RNA, and proteins from biological samples such as blood or tissue. Assay technologies are used to make such isolated bio-molecules visible.

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