Pathology


Highest Sensitivity Liquid Biopsy Test Introduced for Lung Cancer
Approximately 20% of non-small cell lung cancer (NSCLC) patients test positive for an epidermal growth factor receptor (EGFR) driver mutation and receive EGFR Tyrosine Kinase Inhibitor (TKI) therapy, but unfortunately, most will develop a resistance to this type of therapy. More...03 Jan 2017

Ribosomal Protein Expression Specifies Normal and Malignant Human Cells
Proteins are the building blocks of life, produced by molecular machines called ribosomes. A human ribosome is composed of four ribosomal RNAs (rRNAs) and 80 ribosomal proteins (RPs), and its structure is believed to be largely invariant. More...29 Dec 2016

Gene Identified That Drives Deadly Brain Cancer
Glioblastoma is the most common and aggressive brain cancer in adults and over 70% of patients with glioblastoma die within two years of diagnosis, though a gene has been identified that is overactive in a deadly form of brain cancer. More...29 Dec 2016


Proteomic Test Stratifies Patients for Immunotherapies
Anti PD-1 inhibitors are the treatments of choice in second line non-small cell lung cancer (NSCLC), however they only benefit a fraction of patients, while existing biomarkers such as PD-L1 expression correlate with outcomes, but are not sufficient to guide therapy. More...28 Dec 2016

Serum MiR-122 Levels Associated with Histopathological Features of NAFLD
Non-alcoholic steatohepatitis (NASH) can only be diagnosed by the presence of histopathological components, such as steatosis, lobular inflammation, ballooning, and fibrosis and therefore there is a need for non-invasive surrogate markers of histopathological features. More...28 Dec 2016
In Other News
Pneumococcal Immune Status Accurately Determined in Saliva Samples
Measuring Anti-HPV Protein Levels to Predict Recurrence of Oropharyngeal Cancer
Circulating Cell-Free DNA Predicts Gastric Cancer Patients Prognosis
Gram-Negative Bacterial Molecules Associated with Alzheimer Disease Pathology
Antibiotics Prevent Common Hospital-Acquired Infection in Transplant Patients
Prognostic Factors Evaluated for Synchronous Multifocal Necrotizing Fasciitis
Blood Test Could Predict Best Treatment for Lung Cancer
Specific Gene Expression Differentiates Moles from Melanoma
Diagnostic Tool Designed for Familial Mediterranean Fever
Lab Tests Discriminate Bacterial from Nonbacterial COPD Exacerbations
Diagnosing IBD by Evaluating Epigenetic Markers in Blood
Epigenetic Biomarker Predicts Outcome of Childhood Brain Cancer
Multiple Biopsies Recommended for Personalized Breast Cancer Treatments
Genetic Test Significantly Reduces Risk of Cardiovascular Events
Novel Urine Test Predicts High-Risk Cervical Cancer
Human Papilloma Virus Tests Compared and Evaluated
Biomarker Identified for Aggressive Thyroid Cancer
Tumor Cells in Blood Samples Predict Prostate Cancer Spread
Mild-to-Moderate Hypertriglyceridemia Leads to Acute Pancreatitis
Molecular Signature Identified for Aggressive Brain Tumor
Cytosponge Test Could Replace Uncomfortable Endoscopies
Software Platform Provides Capabilities for Somatic Variation Analysis
Personalized Cancer Diagnostics Based on Circulating Tumor DNA Profiling
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.