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Pathology

Image: The new streamlined approach discovered for diagnosing and treating bowel cancer (Photo courtesy of University of Adelaide).

Streamlined Approach Discovered for Treating Bowel Cancer

More than 4,000 Australians die from bowel cancer each year, and more than 17,000 new cases of this cancer will be diagnosed in 2018. Scientists are working to understand the genetic drivers of bowel cancer, with a special interest in those cancers which are the hardest to treat, and which have the poorest prognosis. More...
02 May 2018
Image: The QX200 AutoDG Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules for EvaGreen and probe-based ddPCR applications (Photo courtesy of Bio-Rad).

Molecular Technology Identifies Potential Biomarker for Cancer

For patients with early-stage non-small cell lung cancer (NSCLC), the only recommended treatment option is surgery. After complete resection patients with disease at the same stage experience different outcomes, and within five years a third of patients relapse. More...
26 Apr 2018
Image: A histopathology micrograph of a liver biopsy showing of steatohepatitis showing balloon degeneration of hepatocytes, a form of apoptosis (Photo courtesy of Nephron).

Image Analysis System Quantifies NASH Disease Activity

Non-alcoholic steatohepatitis (NASH) is the progressive form of non-alcoholic fatty liver disease (NAFLD), in which excessive fat accumulates in the liver of individuals who do not have a history of alcohol abuse. More...
25 Apr 2018
Image: A diagram of a normal heart compared to hypertrophic cardiomyopathy (Photo courtesy of the Mayo Clinic).

Genetic Variant Identified As Better Marker for CV Disease

A newly identified subset of a known genetic variant found primarily in individuals of South Asian descent may be a better marker for carriers of heart dysfunction in this population and that individuals with this genetic variant are more likely to develop early signs of hypertrophic cardiomyopathy. More...
24 Apr 2018
Image: Determination of the amyloid‐beta (Aβ) secondary structure distribution in blood plasma by an immuno‐IR‐sensor correlates with PET scanning and CSF markers in Alzheimer\'s disease (AD) patients, with potentials to be an accurate, simple, and minimally invasive biomarker for early AD detection (Photo courtesy of Ruhr University Bochum).

Amyloid Blood Biomarker Detects Alzheimer's Disease

There is, as yet, no cure for Alzheimer's disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention. Alzheimer's disease is thought to begin long before patients show typical symptoms like memory loss. More...
17 Apr 2018
Image: The Vivascope 2500 confocal scanning microscopic view of lymph node metastases from thyroid carcinoma are papillary structures made up of scanty bright spots floating in a dark background (left) (Photo courtesy of IRCSS Santa Maria Nuova Hospital).

Confocal Fluorescence Microscopy Used for Rapid Tissue Evaluation

Optical imaging techniques are currently available for imaging tissues without the need for any type of extensive tissue preparation. There are several applications for their potential use in surgical pathology practice. More...
16 Apr 2018
Image: The use of the WATS3D biopsy is an adjunct to forceps biopsy, identified a patient with abnormality in the esophagus (Photo courtesy of CDx Diagnostics).

Sampling Device Increases Detection of Barrett’s Esophagus

Esophageal adenocarcinoma, one of the most fatal and fastest growing cancers in the USA, can be prevented if detected at a precancerous stage. In Barrett’s esophagus (BE), esophageal squamous mucosa is replaced by metaplastic columnar mucosa predisposed to developing esophageal adenocarcinoma (EAC). More...
12 Apr 2018
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.