Pathology
New Risk Loci Identified for Polycystic Ovary Syndrome
Polycystic ovary syndrome is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. More...09 Jan 2019
Test Detects Protein Associated with Alzheimer’s and CTE
An ultrasensitive test has been developed that detects a corrupted protein associated with Alzheimer’s disease and chronic traumatic encephalopathy (CTE). This advance could lead to early diagnosis of these conditions and how they originate. More...09 Jan 2019
Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing
Exome sequencing is emerging as a first-line diagnostic method in some clinical disciplines, but its usefulness has yet to be examined for most constitutional disorders in adults, including chronic kidney disease, which affects more than 1 in 10 persons globally. More...08 Jan 2019
Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing
Guidelines are rapidly moving toward upfront profiling with next-generation sequencing (NGS) of all advanced lung cancers, but there are still practical issues with this testing method that can limit clinical testing and prevent or delay patients being started on targeted therapies. More...31 Dec 2018
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In Other News
Neuroblastoma Molecular Analysis Leads to Prognostic Markers
Genetic and Epigenetic Features Found in Glioma Tumors
Less-Invasive Biosensor Created for Breast Cancer Diagnosis
Colorectal Cancer Risk Linked to Common and Rare Variants
Inflammatory Bowel Disease Linked to Prostate Cancer
Liquid Biopsy Identifies Advanced Lung Cancer Drivers
Circulating Tumor DNA Detects Early Melanoma Growth
Methylation-Based Liquid Biopsy Test Detects Liver Cancer
Liquid Biopsy Detects Cancer across Multiple Biomarkers
Genes Identified That Predispose People to Chronic Kidney Disease
Levels of IgA Nephropathy Associated with Disease Severity
Sensitive Tumor Detection Uses Cell-Free DNA Methylomes
Biomarker Found for Prostate Cancer Treatment Response
Genetic Basis of Childhood-Onset Cardiomyopathies Identified
Potential Brain Tumor Liquid Biopsies Developed
Genetic Test Helps Patients Avoid Unnecessary Thyroid Surgery
Chromaffin Cell Tumors Diagnosed by Plasma Panel
Breast Cancer Risk Variant Type Determines Tumor Aggressiveness
Generic Test Developed for Early Detection of Cancer
HPV DNA Test Monitors Remission in Oral Cancer
Resistance of Tumor Cells to Cancer Drugs Detected
Dormant Disseminated Tumor Cells Stratified in Breast Cancer Patients
Fatal Prostate Cancer Differentiated from Manageable Cancer
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.