Pathology

Germline Risk Variants Found in Prostate Cancer Patients
Studies done over the past five years or so have unearthed pathogenic germline variants in some 12% to 17% of men with prostate cancer, and such alterations can impact everything from the treatment options available to them, to the management strategies used for other members of the same family. More...21 May 2020

Non-Invasive Blood Assay Can Detect Early Colorectal Cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). In general, colon cancer begins when healthy cells in the colon develop changes (mutations) in their DNA and as the cells accumulate, they form a tumor. More...21 May 2020

Microcytosis Is a Risk Marker of Cancer in Primary Care
Microcytosis is a term used to describe red blood cells that are smaller than normal. Anemia is when there are low numbers of properly functioning red blood cells in the body. In microcytic anemia, the body has fewer red blood cells than normal and those red blood cells it does have are also too small. More...20 May 2020

Rare Kidney Cancer Marked by Molecular Features
Renal medullary carcinoma is a rare cancer of the kidney that predominantly afflicts young people of African descent who carry the sickle cell trait, sickle cell disease, or other sickle hemoglobinopathies that can cause sickling of the red blood cells. More...19 May 2020

Blood Test Shows Promise for Predicting Cancer
Early detection of most cancers is an elusive and daunting task; nevertheless, it has remained a top priority for the cancer research community. Detecting cancer early has manifold advantages: it can increase a patient’s chances of successful treatment, prolong their survival, and substantially improve their quality of life. More...14 May 2020

Bacterial Blood Infections Tied to Heightened Colon Cancer Risk
Colorectal cancer occurs in the colon or the rectum and it is the third most common type of cancer in the USA. Around 90% of cases occur in people aged 50 years or older. As well as age, risk factors include a family history of colorectal cancer, some genetic syndromes, obesity, and a lack of exercise, a diet low in fruit and vegetables, and inflammatory bowel disease. More...12 May 2020

Multicancer Blood Test Aids Screen for Cancer Guide Intervention
As minimally invasive screening tests, liquid biopsies could help reduce cancer-specific morbidity and mortality through earlier detection. However, there is debate on how to effectively screen large populations for cancer, including individuals who do not have symptoms or history of the disease. More...12 May 2020
In Other News
Biomarker Data Improves Risk Prediction for Pancreatic Cancer
Targeted Next-Generation Sequencing Validated for Lysosomal Storage Disorders Diagnosis
Genetic Alterations Analyzed in Pediatric Low-Grade Glioma
Molecular Differences Discovered Among Ovarian Cancer Subgroups
Important Genetic Mechanism Behind Inflammatory Bowel Disease Revealed
Genetic Risk Score Predicts Prostate Cancer Drug Response
Novel Inherited Mutation Predisposes Children to Medulloblastoma
Reactive Pneumocytes Identified by Distinctive Cytology
Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Liquid Biopsy Lung Cancer Screening Method Developed
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
EGFR Mutation Assay Cartridges Evaluated
Prognostic Values of Platelet Parameters in Gynecological Tumors Patients
Combining Biomarkers Predicts Metastasis in Medullary Thyroid Carcinoma
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Combined Biopsy Method Improves Prostate Cancer Diagnosis
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Gut Bacteria Linked to Pulmonary Artery Hypertension
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.