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Microbiology

Image: The geographic distribution of Japanese encephalitis (in red) (Photo courtesy of the CDC – US Centers for Disease Control and Prevention).

Dried Cerebrospinal Fluid Spots Detect Anti-Japanese Encephalitis IgM

The use of filter paper as a simple, inexpensive tool for storage and transportation of blood, “Dried Blood Spots” or Guthrie cards, for diagnostic assays is well-established, but in contrast, there are a paucity of diagnostic evaluations of dried cerebrospinal fluid spots.  More...
29 Mar 2016
Image: The application of metagenomic approaches to define the microbiota of the preterm infant gut and implicate uropathogenic Escherichia coli as a risk factor for necrotizing enterocolitis (NEC) and death (Photo courtesy of Chris Sternal-Johnson).

Uropathogenic Bacteria Linked to Deadly Disease in Preterm Infants

Necrotizing enterocolitis (NEC) is an intestinal disease that afflicts about one in ten extremely premature infants and is fatal in nearly one-third of cases.  More...
28 Mar 2016
Image: The FACSAria III cell sorter instrument (Photo courtesy of BD Biosciences).

Immune Cells Adapt Inefficiently in Patients with Uncontrolled HIV

Antibodies derived from a type of immune cell found in unusually high numbers in human immunodeficiency virus-infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV.  More...
28 Mar 2016
Image: Photomicrograph of a positive indirect fluorescent antibody (IFA) test for Giardia lamblia parasites (Photo courtesy of Dr. Govinda S. Visvesvara).

Methods Compared for Detection of Fecal Giardiasis

Microscopy for intestinal protozoa after formol-ether or formol-ethylacetate concentration is standard procedure for investigating patients with diarrhea where a protozoan etiology is suspected.   More...
27 Mar 2016
Image: A novel nano-biosensor has been developed for lower-cost, rapid virus detection based on upconversion luminescence resonance energy transfer (LRET) technology and DNA oligo hybridization. Testing takes only 2–3 hours, about 10x faster traditional clinical methods (Photo courtesy of the Hong Kong Polytechnic University).

Innovative Nano-Biosensor Developed for Rapid Detection of Viruses

Scientists have invented a compact, easy-to-use biosensor for rapid, sensitive detection of flu and other viruses by utilizing the optical method of upconversion luminescence resonance energy transfer.  More...
23 Mar 2016
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Rapid Low Cost Urine Test Diagnoses Tuberculosis, Reduces Mortality

A low cost, easy to use, urine test to diagnose tuberculosis among patients with human immunodeficiency virus could help reduce the TB death rate of HIV-positive patients in hospital.   More...
21 Mar 2016
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FDA-Cleared Test Detects Carbapenem Resistance Genes

A qualitative in vitro diagnostic test for fast, accurate, and reproducible identification of five distinct families of carbapenem resistance genes that together represent the most common carbapenemases has been approved for marketing.   More...
21 Mar 2016
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.