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Microbiology

Image: A black cartridge containing the innovative paper-based diagnostic for detecting Zika virus: areas that have turned purple indicate samples infected with Zika virus, while yellow areas indicate Zika-free samples (Photo courtesy of Wyss Institute at Harvard University).

CRISPR-based Technology Enables High-Resolution Zika Detection On Low-Cost Paper Discs

Building off their earlier innovative development in “programmable diagnostics”, researchers on an international, multi-institutional team recently joined efforts to quickly prototype their low-cost rapid test with the goal that it could soon be used to screen samples (blood, urine, or saliva) for Zika virus and strain identification. More...
16 May 2016
Image: A smartphone readout from the Polarization Anisotropy Diagnostics (PAD) system reveals the pathogens responsible for an infection and factors such as antibiotic resistance (Photo courtesy of Dr. Chen-Han Huang and Dr. Ki Soo Park, Massachusetts General Hospital).

Microbiologists Display Prototype of Rapid Bacteriological Test Device

A prototype rapid diagnostic device was shown in a proof-of-concept study to identify pathogenic microorganisms with accuracy comparable to that of bacterial culture but with much shorter turnaround time. More...
16 May 2016
Image: A dark field photomicrography reveals the presence of spirochete, or “corkscrew-shaped” bacteria known as Borrelia spp., which is the pathogen responsible for causing Lyme disease (Photo courtesy of Jeffrey Nelson).

New Test Developed For Early Detection Of Lyme Disease

A new test for early detection of Lyme disease (borreliosis) is being developed and this will improve the ability to detect an active infection more easily than before so that healthy people with Lyme disease antibodies in their blood do not receive unnecessary antibiotic treatment and so that appropriate treatments can be initiated at an early stage. More...
12 May 2016
Image: The Specificity of Recombinase Polymerase Amplification -Lateral Flow (RPA-LF) immunochromatographic strip to amplify species of the Viannia subgenus. The most relevant L. Viannia species (L. braziliensis, L. guyanensis, and L. panamensis) produced stronger bands in the lateral flow strip than other less common species of this subgenus. NTC= No template control (Photo courtesy of University of Texas Medical Branch).

Field-Applicable Molecular Test Diagnoses Tegumentary Leishmaniasis

Cutaneous and mucosal leishmaniases are widely distributed in Central and South America. Leishmania of the Viannia subgenus are the most frequent species infecting humans. L. (V.) braziliensis, L. (V.) panamensis are also responsible for metastatic mucosal leishmaniasis. More...
11 May 2016

Bacterial Vaginosis Assessed By Molecular Methods

Bacterial vaginosis (BV) is an aberrant state of the vaginal microbiota, which is characterized by a depletion of lactobacilli, an increased diversity of the bacterial population and an elevated pH. It is one the most common vaginal syndromes in fertile, premenopausal and pregnant women. More...
11 May 2016

A More Comprehensive Approach to Identifying Patients with Mononucleosis

A new systematic review provides advice for earlier, more accurate diagnosis of patients with infectious mononucleosis to help expedite proper treatment. More...
10 May 2016

Zika Test Authorized by FDA for Emergency Use

The first test from a commercial lab provider to receive the US Food & Drug Administration (FDA)’s Emergency Use Authorization (EUA) for testing patients in the USA, including Puerto Rico, for Zika infection. The molecular test is intended for the qualitative detection of RNA from the Zika virus in human serum specimens from certain individuals. More...
10 May 2016
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.