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Microbiology

Image: Immunohistochemical detection of human intestinal spirochetosis with signs of invasion (Photo courtesy of the US National Institute of Health).

Anti-Treponema Immunohistochemistry Cross-Reactivity Reported with Non-Treponema Spirochetes

Syphilis has different histopathologic presentations, and it can mimic a significant number of entities while human intestinal spirochetosis is characterized by the presence of a layer of spirochetes adherent to the apical epithelial surface of the colorectal mucosa. More...
12 Oct 2016
Image: Proteins from Rift Valley fever virus (Photo courtesy of Medical Xpress).

Mosquito-Borne Rift Valley Fever Virus Linked to Miscarriage in Humans

Rift Valley fever virus (RVFv) has been linked to miscarriage in a cross-sectional study of pregnant Sudanese women with fever, which indicated a 7 times greater risk of miscarriage for infected women. More...
11 Oct 2016
Image: A depiction of a surface view of coronavirus, which has now been linked to neurological disease (Image courtesy of the Institut National de la Recherche Scientifique).

Coronavirus Linked to Neurological Disease in Humans

A case-study of fatal encephalitis has, for the first time, led researchers to discover a direct association with strain OC 43 of the human coronavirus (HCoV), providing confirmatory evidence for the hypothesis that this respiratory virus can cause certain neurological diseases of unknown origin such as multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, and encephalitis. More...
11 Oct 2016
Image: A formulated custom TaqMan array card (Photo courtesy of Thermo Fisher Scientific).

Quantitative Molecular Diagnostic Methods Identify Causes of Childhood Diarrhea

The number of cases of childhood diarrhea attributed to pathogens such as bacteria, parasites, viruses or other infections has been substantially underestimated and may be nearly twice as high as previous analysis suggests. More...
06 Oct 2016
Image: Gradient maps of uninfected RBC and RBCs infected by P. falciparum in early trophozoite, late trophozoite, and schizont stages (scale bar = 5µm) (Photo courtesy of Duke University).

New Technology Quickly Diagnoses Malaria

The gold standard for malaria diagnosis is manual microscopic evaluation of Giemsa stained blood smears; however, the utility of this approach is limited by the skill of an expert microscopist. Further, both the staining process and microscopic examination can be time consuming. More...
06 Oct 2016
Image: A photomicrograph of Leptospirosis bacteria magnified ×200 in a dark field optical microscope (Photo courtesy Dr. Steve H Fisyh).

Extended Multilocus Sequence Typing Developed for Leptospirosis

Leptospirosis is a zoonotic disease caused by pathogenic species of Leptospira that can be carried naturally by most mammalian species and transmission to humans most commonly occurs via direct animal contact or via water contaminated with animal urine. More...
05 Oct 2016
Image: The T-SPOT.TB Interferon-gamma release assay for tuberculosis screening (Photo courtesy of Oxford Immunotec Global).

Screening for Latent Tuberculosis Infection Recommended

Tuberculosis remains an important preventable disease, including active tuberculosis infection, which may be infectious and latent infection (LTBI), which is asymptomatic and not infectious, but can later reactivate and progress to active disease. More...
29 Sep 2016
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.