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Microbiology

Image: Schematic of an array of nanotubes decorated with gold nanoparticles that capture virus molecules for in situ Raman spectroscopy for label-free optical virus identification (Photo courtesy of Professor Mauricio Terrones)

Fast and Inexpensive Device Captures and Identifies Viruses

 Currently, virologists estimate that 1.67 million unknown viruses are in animals, a number of which can be transmitted to humans. Known viruses, such as H5N1, Zika and Ebola have caused widespread illness and death. Early detection could halt virus spread by enabling rapid deployment of countermeasures. More...
07 Jan 2020
Image: Design of the CareStart G6PD deficiency screening test and interpretation of the results:  Panel A, no color change for sample with deficient G6PD enzymatic activity; Panel B, distinct purple color for sample with normal G6PD enzymatic activity (Photo courtesy of Charles Darwin University).

Rapid Diagnostic Test for The Detection of G6PD Deficiency Evaluated

 To reduce the risk of drug-induced hemolysis, all patients should be tested for glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDd) prior to prescribing primaquine (PQ)-based radical cure for the treatment of vivax malaria. More...
07 Jan 2020
Image: The Diagnostic Performance of C6 Enzyme Immunoassay for Lyme Arthritis has been evaluated (Photo courtesy of Lonnie R. Marcum, PT, BSHCA)

Immunoassay May Help Identify Pediatric Lyme Arthritis

 In the USA, Lyme arthritis is the most common feature of late stage infection with the tick-borne spirochete, Borrelia burgdorferi, usually beginning months after the initial tick bite. Patients with Lyme arthritis have intermittent or persistent attacks of joint swelling and pain in one or a few large joints, especially the knee, usually over a period of several years, without prominent systemic manifestations. More...
07 Jan 2020
Image: Flongle is an adapter (flow cell dongle) for the MinION or GridION that enables direct, real-time DNA or RNA sequencing on smaller, single-use flow cells (Photo courtesy of Oxford Nanopore Technologies).

Nanopore Sequencing Rapidly Diagnoses Gut Condition in Preterm Infants

 The culture-independent, sensitive, data-rich nature of metagenomic sequencing, combined with powerful bioinformatics tools, have allowed scientists to differentiate patient groups from healthy individuals based on their microbial profiles. More...
03 Jan 2020
Image: The NUCLISENS EASYMAG instrument is designed to meet the most critical needs when it comes to premium quality total nucleic acid extraction. The system automates an enhanced magnetic silica version of BOOM technology, a gold standard for efficient universal extraction of RNA and DNA (Photo courtesy of bioMérieux).

Asthma Severity Linked to Microbiome of Upper Airway

More than six million children under the age 18 have asthma in the USA. Asthma exacerbations have high impact on children, their families, the health care system, and may lead to subsequent decline in lung function. More...
01 Jan 2020
Image: Point-of-care serodiagnostic test for early-stage Lyme disease using a multiplexed paper-based immunoassay and machine learning (Photo courtesy of American Chemical Society).

Paper-Based Test Could Diagnose Lyme Disease at Early Stages

 Caused by the tick-borne spirochete Borrelia burgdorferi, Lyme disease (LD) is the most common vector-borne infectious disease in North America and Europe and timely diagnosis and treatment are effective in preventing disease progression. More...
01 Jan 2020
Image: The C. DIFF QUIK CHEK COMPLETE test is a rapid membrane enzyme immunoassay for the simultaneous detection of Clostridium difficile glutamate dehydrogenase antigen and toxins A and B in a single reaction well (Photo courtesy of Abbott)

C. Diff Carriers Are Source of Infections in Hospitals

 Clostridioides difficile is a spore-forming, gram-positive anaerobic bacillus spread by fecal–oral transmission of spores, which remain viable for long periods of time ex vivo. Although C. difficile carriers do not have diarrhea, they do shed spores that can contaminate environmental surfaces. More...
26 Dec 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.