Immunology

Urinary Antigen Test Kit Evaluated for Diagnosing Legionella Pneumonia
Legionellosis is caused by bacteria called Legionella. The disease has two different forms. Legionnaires’ disease is the more severe form of infection that causes pneumonia. Pontiac fever is caused by the same bacteria, but is a milder illness without pneumonia. More...24 Feb 2021

Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma
Glioblastoma (GBM) is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. Glioblastoma can occur at any age, but tends to occur more often in older adults. It can cause worsening headaches, nausea, vomiting and seizures. More...23 Feb 2021

T Cell Response Profiled in COVID-19 Patients
The clinical spectrum of SARS-CoV-2 infection is highly variable, spanning from asymptomatic or subclinical infection, to severe or fatal disease. Characterization of the immune response to SARS-CoV-2 is urgently needed in order to better inform more effective treatment strategies, including antivirals and rationally designed vaccines. More...22 Feb 2021

Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and currently the third leading cause of cancer deaths in the USA. Despite the fact that it only accounts for about 3% of new cancer cases, it is responsible for more than 7% of all cancer deaths, and only10% of patients survive five years with the disease. More...17 Feb 2021

Blood Test Distinguishes Epileptic Seizures From PNES
Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of awareness. Epilepsy affects both males and females of all races, ethnic backgrounds and ages. More...16 Feb 2021

TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
Mild to moderate bleeding disorders (MBDs) are characterized by symptoms such as epistaxis, easy bruising, or menorrhagia, but bleeding can also be severe under certain circumstances such as hemorrhage after surgery or birth. More...11 Feb 2021

New Control Mechanism Discovered in Innate Immune System
Proteases are enzymes that cleave other proteins. Most often, proteases occur in cascade networks, where a particular event triggers a chain reaction in which several proteases cleave and thereby activate each other. Most well-known is probably the coagulation cascade, which causes clotting of our blood when a vessel is punctured. More...11 Feb 2021
In Other News
Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes
Early Plasma Biomarkers Discovered for Alzheimer's Disease
Proinflammatory T Cell Polarization Investigated in Early Knee Osteoarthritis
Alzheimer's Progression Tracked with Blood Biomarkers
Early Differences in Cytokine Production Distinguish Severity of COVID-19
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Basophil Activation Test Predicts Pediatric Wheezing Prognosis
Increased Serum Neurofilament Light Portend Worse Prognosis in COVID-19
Immunohistological Detection of Small Particles of Echinococcus Species Evaluated
Serum Pentosidine Levels Measured in Systemic Lupus Erythematosus
Angiopoietin-Like 2 Is a Biomarker for Diabetic Foot Patients
Combination Urinary Biomarker Panel Detects Pancreatic Cancer Earlier
Chitotriosidase Expression in Sarcoidosis Limited by Gene Expression
Preliminary Predictive Criteria Identified for COVID-19 Cytokine Storm
Multiplex Bead-Based Immunoassay Validated for Non-Invasive Bladder Cancer Detection
Chronic Lymphocytic Leukemia Increases Peripheral Blood Hematopoietic Stem Cells
Novel Biomarkers Predict the Development of Incident Heart Failure
Osteopontin Linked to Progressive Lung Scarring in Scleroderma Patients
Scrub Typhus Enzyme Linked Immunoassay Evaluated for Accuracy
Newly Developed Immunoassay Evaluated for Infectious Diseases
Novel Biomarker Candidate for Amyotrophic Lateral Sclerosis Explored
Elevated Soluble C5b9 Biomarker Found in SARS-Cov-2 Infected Children
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.