Immunology

Plasma-Based S100B Testing for Management of Traumatic Brain Injury
Traumatic brain injury (TBI) usually results from a violent blow or jolt to the head or body. An object that penetrates brain tissue, such as a bullet or shattered piece of skull, also can cause traumatic brain injury. Mild traumatic brain injury may affect the brain cells temporarily. More...24 May 2021

Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn’s Disease
Crohn's disease and ulcerative colitis, another type of inflammatory bowel disease (IBD), are characterized by dysregulated adaptive immune responses to the microbiota in genetically susceptible individuals, but the human specificity of these responses had so far been largely undefined. More...20 May 2021

Potential Immune Markers Found for Active Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those affected. More...18 May 2021

Maternal Multiomic Changes Could Predict Onset of Labor
Currently, predictions of when labor will start are imprecise and based on gestational age and an average pregnancy length of 40 weeks, even though the onset of labor between week 37 and 42 of pregnancy is considered normal. Having a better idea of when labor may arrive could help with planning and managing medical concerns like fetal lung maturation. More...18 May 2021


Gel and Capillary Electrophoresis Compared for Human Proteins
The electrophoresis of serum proteins remains a laboratory cornerstone for the diagnosis and monitoring of patients with plasma cell disorders, such as monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, and AL amyloidosis. More...12 May 2021

Developed Immunoassay Predicts Benefits of Anti-PD-1 Therapy in NSCLC
Lung cancer is the most common cause of cancer-related deaths worldwide. However, current targeted therapies and immunotherapies have gradually improved patient survival. Anti-programmed cell death-1 (PD-1) antibodies (Abs) are key drugs in non-small-cell lung cancer treatment; however, clinical benefits with anti-PD-1 monotherapy are limited. More...12 May 2021
In Other News
Synovial Fluid Neutrophils Phenotyped in Oligoarticular Juvenile Idiopathic Arthritis
ANGPTL8 Levels Associated with Hyperlipidemia in Primary Nephrotic Syndrome
Serum α-L-Fucosidase Activity Measured for COVID-19 Infection
Urinary Heat Shock Protein 70 Evaluated in Chronic Prostatitis
Breath Test Determines Severity of Methylmalonic Acidemia Disease
Snibe Diagnostic’s Maglumi HIV Ab/Ag Combi CLIA Assay (4th-Generation) Secures CE Mark (List A)
Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality
T Cells Recognize Recent SARS-CoV-2 Variants
Type 1 Diabetes Onset Preceded by Gene Expression Changes
Serious Infections Prevalent in ANCA-Associated Vasculitis
Immunoassay Developed for Quantitative Detection of Serum Interleukin‐6
Performance of Five Lipoprotein(a) Immunoassays Evaluated
Flow-Cytometric Expression of Endoglin Assessed in B-Acute Lymphoblastic Leukemia
Toxoplasmosis Immune Status in Pregnancy Determined by Immunochromatography Assay
Toxoplasmic Encephalitis in HIV Patients Detected in Urine
Paraproteins Identification Methods Compared for Monoclonal Gammopathies
Chemiluminescence Anti‐Müllerian Hormone Assay Performance Characterized
Cardiac Troponins Assessed for Acute Heart Failure
Biomarker Protein Investigated in Juvenile Idiopathic Arthritis
Immune Response to Insulin Identifies Risk of Juvenile-Diabetes
Fibrinogen to Albumin Ratio Reflects ANCA‐Associated Vasculitis Activity
Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients
Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.