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Immunology

Image: The Phadia  250 Immunoassay Analyzer: Automated processing of EliA and ImmunoCAP assays (Photo courtesy of Thermo Fisher Scientific).

Antinuclear Antibody Tests Compared for Systemic Autoimmune Rheumatic Diseases

Systemic autoimmune rheumatic diseases, also known as connective tissue diseases (CTD), including all diseases triggered by the formation of immune complexes that enter the circulation, are then deposited in different tissues and organs, and cause damage. More...
05 Oct 2021
Image: Histopathology photomicrograph of lymphocytic esophagitis: Esophageal mucosa showing peripapillary intraepithelial lymphocytosis with basal zone hyperplasia and intercellular edema. No significant population of eosinophils or neutrophils is identified (Photo courtesy of Yusuf Kasirye, MD, et al)

CD8 T-Cell–Predominant Lymphocytic Esophagitis Associated with GERD

In patients with reflux esophagitis (RE), increased lymphocytes are often part of a mixed inflammatory infiltrate that also includes eosinophils and/or neutrophils. Less frequently, lymphocytes are the only type of inflammatory cells associated with gastroesophageal reflux disease (GERD). More...
05 Oct 2021
Image: The Pylon 3D Fully Automated Immunoassay System (Photo courtesy of ET Healthcare)

Novel Assay Measures Interleukin-6 in Whole Blood Samples

Interleukin 6 (IL-6) is a pleiotropic cytokine produced by various stromal cells and immune system cells, involved in inflammation and infection responses, regeneration process, metabolism regulation, bone homeostasis, and neural functions. More...
05 Oct 2021
Image: Next Generation Phenotyping Platform from Selux (Photo courtesy of Selux Diagnostics, Inc.)

Next Generation Rapid Antibiotic Susceptibility Testing (AST) Platform Granted FDA Breakthrough Device Designation

Selux Diagnostics, Inc.’s (Boston, MA, USA) Next Generation Phenotyping (NGP) platform has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA) for positive blood culture and sterile body fluid samples. More...
05 Oct 2021
Image: Photomicrograph of a bone marrow smear from a patient with hemophagocytic lymphohistiocytosis, showing foamy macrophages engulfing mature and precursor erythrocytes (arrow) (Photo courtesy of Ismail Hader, MD, FACP)

IFN-γ Signature Distinguishes Pediatric Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS

Hemophagocytic lymphohistiocytosis (HLH), severe sepsis, and persistent systemic inflammatory response syndrome are all conditions defined by excessive immune activation that may progress rapidly and are associated high risk of death without early introduction of appropriate therapy. More...
04 Oct 2021
Image: Siemens Healthineers’ new Atellica VTLi patient-side immunoassay analyzer (Photo courtesy of Siemens Healthineers)

Siemens Wireless, Handheld Patient-Side Immunoassay Analyzer Enables Industry First Fingerstick High-Sensitivity hs-cTnI Testing at POC

Siemens Healthineers’ (Erlangen, Germany) new Atellica VTLi patient-side immunoassay analyzer marks a vital leap forward in cardiac testing by offering clinicians the first high-sensitivity troponin I test from a fingerstick sample at the point of care. More...
30 Sep 2021
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New Non-Invasive Saliva Test for Early and Accurate Detection of Prostate Cancer Presented at AACC 2021

A new non-invasive test that uses saliva samples to accurately diagnose cases of prostate cancer was presented at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo. More...
29 Sep 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.