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Immunology

Image: Scanning electron micrograph of Human T-cell Lymphotropic Virus-1 (HTLV-I) (green) infecting a human T-lymphocyte (yellow) (Photo courtesy of Dr. Dennis Kunkel).

Test Confirms Presence of Human T-Cell Lymphotropic Virus-I/II Antibodies

A supplemental test for Human T-cell Lymphotropic Virus-I/II has been licensed and is intended for use as an additional, more specific test for human serum or plasma specimens that have previously tested positive on other HTLV-I/II blood donor screening tests.  More...
29 Dec 2014
Image: The MRX Microplate Reader for enzyme-linked immunosorbent assays (Photo courtesy of Dynatech Laboratories).

Antibody Test Predicts Cold-Related Asthma Attacks

A diagnostic marker can be used to identify the risk group for asthma attacks caused by rhinoviruses and this can be assessed with a simple antibody test.  More...
17 Dec 2014
Image: The OnSite Chikungunya IgM Combo Rapid Test (Photo courtesy of CTK Biotech Inc.).

Serologic Diagnostic Tests Evaluated for Chikungunya Virus

The disease caused by the mosquito borne Chikungunya virus is clinically characterized by sudden-onset fever and severe arthralgia, which may persist for weeks, months, or years after the acute phase of the infection.   More...
03 Dec 2014
Image:  Diagram of pathological changes in a glomerulus (visible via electron microscopy) in membranous nephropathy.  Black - immune complex; Dark Purple - basement membrane; Pink – endothelium; Green - visceral epithelium; Light Purple - mesangial cells (Photo by M. Komorniczak and Huckfinne, courtesy of Wikimedia).

Second Protein Identified for Common Kidney Failure

An international team of researchers has found a second protein, THSD7A, associated with a common form of kidney failure—the autoimmune “membranous nephropathy.” The discovery is likely to provide an important new biomarker for the disease.  More...
01 Dec 2014
Image: Histopathology of ovarian serous papillary borderline tumor, intracystic, without surface cortical involvement (Photo courtesy of Brown University).

Prognostic Biomarker Candidates Identified for Ovarian Cancer

Two independent classes of novel candidate prognostic markers for ovarian cancer have been identified advancing efforts to develop targeted therapies for the disease.  More...
25 Nov 2014
Image: The MRX II microplate reader (Photo courtesy of Dynex Technologies).

Prognostic Biomarker Found for Post-Chemotherapeutic Relapse in Visceral Leishmaniasis

The effective clinical management, chemotherapy and control of the transmission of visceral leishmaniasis are largely dependent on early and unequivocal diagnosis as without effective chemotherapy symptomatic VL is usually fatal.  More...
05 Nov 2014
Image: Immunohistochemistry of lung tissue positive for anaplastic lymphoma kinase in non-small-cell lung cancer (Photo courtesy of Ventana Medical Systems).

Anaplastic Lymphoma Kinase Immunohistochemistry Compares with FISH Testing

The detection of anaplastic lymphoma kinase-gene rearrangements in non–small-cell lung cancer is mainly performed by fluorescence in situ hybridization.  More...
05 Nov 2014
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.