Hematology
Anticoagulant Adjustment Evaluated Using Different Prothrombin Time Tests
Preanalytical variables may affect the results of routine coagulation assays. One important variable is hematocrit (Ht), which affects coagulation testing results. A sample with high Ht has lower plasma quantity, resulting in a dilution effect on the sample by an excess of the anticoagulant sodium citrate. More...26 Nov 2020
CD200 Expression Marks Leukemia Stem Cells in Human AML
Acute myeloid leukemia (AML) is organized as a hierarchy sustained by a minor population of leukemia stem cells (LSCs) with self-renewal capacity that drive disease. The LSC populations of AML exhibit phenotypic, genetic, and functional heterogeneity that contribute to therapy failure and relapse. More...17 Nov 2020
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
Severe adult-onset autoinflammatory disorders often manifest with overlapping clinical features. Affected individuals may develop episodes of high, spiking fevers, a pink or salmon colored rash, joint pain, muscle pain, a sore throat and other symptoms associated with systemic inflammatory disease. More...12 Nov 2020
Paper Diagnostic Directly Measures Fibrinogen in Whole Blood
Fibrinogen is a protein found in blood that is needed for clotting. When a patient experiences traumatic injury, such as a serious car accident, or major surgery and childbirth complications, fibrinogen is required in their blood to prevent major hemorrhaging and death from blood loss. More...10 Nov 2020
Newborns Getting Preoperative Blood Transfusions Have More Complications
Blood transfusions in the neonatal patient population are common, but there are no established guidelines regarding transfusion thresholds. Little is known about postoperative outcomes in neonates who receive preoperative blood transfusions (PBTs). More...05 Nov 2020
Single-Cell Sequencing Reveals Clonal Diversity Among AML Patients
A growing body of evidence supports the role of clonal diversity in therapeutic resistance, recurrence, and poor outcomes in cancer. Clonal diversity also reflects the history of the accumulation of somatic mutations within a tumor. More...03 Nov 2020
Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes
The age-related acquisition of somatic mutations that lead to clonal expansion in regenerating hematopoietic stem cell populations has recently been associated with both hematological cancer and coronary heart disease, and this phenomenon is termed clonal hematopoiesis of indeterminate potential (CHIP). More...29 Oct 2020
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Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma
Elevated Clotting Factor V Found with Severe COVID-19
RBC Distribution Width Associated with COVID-19 Mortality Risk
Microfluidic Label-Free Bioprocessing of Reticulocytes from Erythroid Culture
New Diagnosed Anemia Linked to Crohn’s Disease Risk
Hematological Parameters Evaluated for Cervicocranial Arterial Dissection Stroke
Quantitative Agglutination Determined on Automatic Hematology Analyzer
Complex ABO Glycan Phenotypes Predicted by Lectin Microarrays
Positive Lymphocyte Gene Rearrangement Evaluated for Hematologic Malignancies
Lymphocyte Count Correlated to Comorbid Diabetes and COVID-19
Clonal Hematopoiesis Prevalence Determined in Healthy Donors
Hodgkin Lymphoma Therapy Response Linked to T-Cell Receptor Repertoire
Microfluidic Device Explores Ovarian Cancer Interactions
Biomarkers Evaluated for Severity of Diabetic Kidney Disease
Nanoparticle System Captures Heart-Disease Biomarker From Blood
Blood Bank NAT-Based Assay Prevents Transfusion-Transmitted Malaria
Elevated Glycolated Hemoglobin in Young People Predicts Likelihood of Diabetes or Cardiovascular Disease in Adulthood
High Blood Glucose Tied to Cardiovascular Risk in Diabetes
IFN‐γ Release Assay Helps Diagnose Hemophagocytic Lymphohistiocytosis
Automated Malaria Diagnosis Enhanced by Deep Neural Networks
Eosinophil Count Provides Diagnostic Information for COVID-19
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.