Hematology


Hypersegmented Neutrophils Associated with Reduced Lung Function
Neutrophils are phagocytic innate immune cells, which patrol the blood vessels and become activated in response to inflammatory triggers. Activation results in neutrophil migration to the site of infection, where pathogens can be eliminated by phagocytosis or NETosis. More...19 Feb 2019


Automated Malaria Diagnosis Evaluated Using Autoanalyzer
Early and accurate diagnosis of malaria is a critical aspect of efforts to control the disease, and several diagnostic tools are available. Microscopic assessment of a peripheral blood smear enables direct visualization of parasites in infected red blood cells and is the clinical diagnostic gold standard. More...04 Feb 2019

Tumor Sequencing Finds Mutations Caused by Blood Disorder
Clinical sequencing assays aim to identify somatic mutations in cancer cells for accurate diagnosis and treatment. However, most clinical-grade implementations lack patient-matched germline DNA, and supplemental analyses are needed to infer the mutational status of variants. More...15 Jan 2019

New Definition for Plasma Cell Leukemia Proposed
Plasma cell leukemia (PCL) is an uncommon but aggressive malignancy that accounts for 1% to 2% of all plasma cell dyscrasias. PCL has been defined as the presence of ≥ 20% circulating plasma cells (CPCs) on conventional white blood cell differential count and an absolute plasma cell count of ≥ 2 × 109/L in the peripheral blood. More...09 Jan 2019

Howell-Jolly Body-Like Inclusions Correlated with Myelodysplastic Syndrome
Howell-Jolly body–like inclusions have been previously associated with patients who are human immunodeficiency virus (HIV) infected, taking antiviral medications, and immunosuppressed. These inclusions appear in neutrophils and resemble Howell-Jolly bodies of normoblasts in abnormal erythropoiesis. More...07 Jan 2019
In Other News
Genetic Marker Predicts Early Relapse in Pediatric ALL
Macrocytic Anemia Associated with HBV Liver Impairment Severity
Potential Screening for Tailoring Treatment of AML
Unique Genetic Makeup of Myeloma Tumor Cells Profiled
Plasmodium vivax Isolated in Duffy Negative Individuals
Transfusions with Older Blood Linked to Adverse Events
Acute Myeloid Leukemia Regulatory Networks Identified
Malaria Parasitaemia Correlated with Monocyte to Lymphocyte Ratio
Rapid Test for Sickle-Cell Disease Evaluated
RNA Defects Linked to Multiple Myeloma Progression
Blood Compatibility Assay Approved by FDA
Functional Genomic Landscape of AML Analyzed
Myeloproliferative Neoplasms Fall into Genetic Subgroups
Prognostic Value of Blood Cell Counts Investigated
Multiple Myeloma Subtypes Linked to Patient Ancestry
Molecular Diagnostics Prevents Malaria in Blood Banks
Next-Gen Test Authorized for Minimal Residual Disease
Automated Microscopy Compared for Routine Malaria Diagnosis
Disease Progression Apprised by Post-Treatment Mutation Sequencing
DNA Test Predicts Risk of Leukemia Relapse
Biomarker Identified for Novel Asthma Treatment
New mRNA Cancer Drivers Revealed in Chronic Lymphocytic Leukemia
Blood Test Predicts Lymphoma Therapy Success
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.