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Hematology

Image: The Gallios flow cytometer provides efficient acquisition of superior quality data from up to 10 colors with advanced optical design for enhanced sensitivity for multicolor assays (Photo courtesy of Beckman Coulter).

Minimal Residual Disease Assessed in AL Amyloidosis Patients

 Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis in the USA. Despite achieving a hematologic complete response after treatment, many patients with AL amyloidosis do not attain recovery of organ function and/or experience hematologic relapse. More...
17 Mar 2020
Image: The composition of patients` microbiomes can predict their clinical outcomes when undergoing stem cell transplants (Photo courtesy of European Leukemia Net).

Microbiome Composition Predicts Outcome Among Stem Cell Transplant Patients

 Allogeneic hematopoietic stem cell transplants are common among patients with blood cancers, and while they may cure the disease, such transplants can also lead to complications such as graft-versus-host disease and infections. More...
12 Mar 2020
Image: The Gen‐S hematology analyzer provides a complete blood count, a five-part differential leukocyte count, and a reticulocyte count (Photo courtesy of InCav).

Predictors Evaluated for Microalbuminuria in Type 2 Diabetes

 Chronic inflammation has an important role in the development and progression of type 2 diabetes through immunologic inflammatory mechanisms. The neutrophil‐to‐lymphocyte ratio (NLR) is a new, simple, and inexpensive marker of subclinical inflammation and has been used as a systemic inflammatory marker in chronic diseases. More...
12 Mar 2020
Image: PAX5/CD103 dual immunohistochemistry (IHC) staining showing no definite dual-positive cells, PAX5 stain showing brown nuclear staining in nonneoplastic B cells and CD103 showing membranous and cytoplasmic staining in a subset of T cells (Photo courtesy of US National Institute of Cancer).

Dual Immunohistochemistry Bone Marrow Staining Detects Hairy Cell Leukemia

 Hairy cell leukemia (HCL) is a B-cell lymphoproliferative disorder characterized by distinct immunophenotype (positive for CD19, CD20, PAX5, CD22, CD11c, CD25, CD103, CD123, and CD200). Immunophenotypic analysis by flow cytometry (FC) is considered the gold standard for diagnosis of HCL. More...
03 Mar 2020
Image: Peripheral blood smear from a patient with myelodysplastic syndrome showing macrocytic and hyperchromic anemia (cross), hypersegmented neutrophil (arrow) and moderate thrombocytopenia (Photo courtesy of Jong-Hwa Kim, MD, PhD).

Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis

 Myelodysplastic syndromes (MDS) are clonal myeloid malignancies arising from hematopoietic stem cells (HSCs), which are characterized by bone marrow (BM) ineffective hematopoiesis, peripheral blood cytopenias, and a propensity to transform to acute myeloid leukemia (AML). More...
03 Mar 2020
Image: The VisuLize Factor XI ELISA Kit is an Enzyme Immunoassay for the quantitative determination of Factor XI Antigen in human plasma samples using the double antibody enzyme linked immuno-sorbent assay (ELISA) (Photo courtesy of Affinity Biologicals, Inc).

Factor IX Inhibitor Incidence in Pediatric Hemophilia B Examined

 Hemophilia B is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (hemophilia A). More...
20 Feb 2020
Image: The BCS XP System is one of the most widely used fully automated hemostasis analyzers, delivers accurate and precise results (Photo courtesy of Siemens Healthcare).

Physical Activity and Thrombophilic Risk Investigated

 Among the effects of physical exercise on coagulation, the influence on protein anticoagulant system and PC deficiency-related thrombophilic risk are still controversial. The impact of physical activity on the coagulation system has been described. More...
18 Feb 2020
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.