Hematology

Minimal Residual Disease Assessed in AL Amyloidosis Patients
Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis in the USA. Despite achieving a hematologic complete response after treatment, many patients with AL amyloidosis do not attain recovery of organ function and/or experience hematologic relapse. More...17 Mar 2020

Microbiome Composition Predicts Outcome Among Stem Cell Transplant Patients
Allogeneic hematopoietic stem cell transplants are common among patients with blood cancers, and while they may cure the disease, such transplants can also lead to complications such as graft-versus-host disease and infections. More...12 Mar 2020

Predictors Evaluated for Microalbuminuria in Type 2 Diabetes
Chronic inflammation has an important role in the development and progression of type 2 diabetes through immunologic inflammatory mechanisms. The neutrophil‐to‐lymphocyte ratio (NLR) is a new, simple, and inexpensive marker of subclinical inflammation and has been used as a systemic inflammatory marker in chronic diseases. More...12 Mar 2020

Dual Immunohistochemistry Bone Marrow Staining Detects Hairy Cell Leukemia
Hairy cell leukemia (HCL) is a B-cell lymphoproliferative disorder characterized by distinct immunophenotype (positive for CD19, CD20, PAX5, CD22, CD11c, CD25, CD103, CD123, and CD200). Immunophenotypic analysis by flow cytometry (FC) is considered the gold standard for diagnosis of HCL. More...03 Mar 2020

Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis
Myelodysplastic syndromes (MDS) are clonal myeloid malignancies arising from hematopoietic stem cells (HSCs), which are characterized by bone marrow (BM) ineffective hematopoiesis, peripheral blood cytopenias, and a propensity to transform to acute myeloid leukemia (AML). More...03 Mar 2020

Factor IX Inhibitor Incidence in Pediatric Hemophilia B Examined
Hemophilia B is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (hemophilia A). More...20 Feb 2020

Physical Activity and Thrombophilic Risk Investigated
Among the effects of physical exercise on coagulation, the influence on protein anticoagulant system and PC deficiency-related thrombophilic risk are still controversial. The impact of physical activity on the coagulation system has been described. More...18 Feb 2020
In Other News
Direct Oral Anticoagulants Determined by RDT in Urine Samples
Immune Profiles Analyzed in Acute Myeloid Leukemia Bone Marrow
Bone Marrow Donors May Transfer Pathogenic Mutations to Patients
Metabolic Syndrome Associated with Increased Blood Clot Recurrence Risk
Diagnostic Assay Identifies Leukemic Stem Cells
Glycoprotein-Specific Direct Platelet Autoantibody Testing in Immune Thrombocytopenia
Biomarker Predicts Prognosis in Acute Myeloid Leukemia Patients
Molecular Profiles, Microenvironment Signatures May Improve Lymphoma Prognosis
Immature Natural Killer Cells Predict Relapse After Cord Blood Transplantation
Hypercoagulability Evaluated in New‐Onset Systemic Lupus Erythematosus Patients
Germline Genetic Testing Assesses Inherited Risk for Myeloid Malignancies
Hepatic Dysfunction and Coagulopathy Quantified in Fatal Dengue Fever
Distinct Myelodysplastic Syndrome Subtypes Identified by Genomic, Transcriptomic Analysis
Fresh Red Blood Cells Transfusions No Better Than Older Ones
Single-Cell Analysis Uncovers Regulatory Program in Rare Leukemia
Autoimmunity Markers Prevalence Assessed in Immune Thrombocytopenia
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Coagulation Function Explored for Gestational Diabetes Hemorrhage Risk
Hemophilia B Gene Increases Risk for Postpartum Bleeding
Acute Myeloid Leukemia Diagnosed by Convolutional Neural Networks
Next Generation Glycated Hemoglobin Assay Evaluated
Second Malignancy Risk Higher for Some Leukemia Survivors
Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.