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Hematology

Image: Schematic diagram of the fully-automatic blood-typing chip exploiting bubbles for quick dilution and detection (Photo courtesy of Tokyo University of Science).

Micro-Lab on a Chip Detects Blood Type Within Minutes

Blood transfusion, if performed promptly, is a potentially life-saving intervention for someone losing a lot of blood. However, blood comes in several types, some of which are incompatible with others. Transfusing an incompatible blood type can severely harm a patient. More...
27 Jul 2020
Image: An ACL TOP Hemostasis Testing System (Photo courtesy of Instrumentation Laboratory).

Endotheliopathy Assessed in COVID-19-Associated Coagulopathy

An important feature of severe acute respiratory syndrome coronavirus 2 pathogenesis is COVID-19-associated coagulopathy, characterized by increased thrombotic and microvascular complications. COVID-19 infection coagulopathy is characterized by high D-dimer and fibrinogen concentrations with minor changes in prothrombin time and platelet count. More...
23 Jul 2020
Image: A scanning electron microscope image of normal circulating human blood showing red blood cells, several types of white blood cells including lymphocytes, a monocyte, a neutrophil and many small disc-shaped platelets (Photo courtesy of [U.S.] National Cancer Institute)

COVID-19 Patients with Lymphocytopenia Are Likely to Suffer Severe Disease Symptoms

An easily recognizable feature in blood samples may be an indicator of whether a COVID-19 patient will be likely to suffer from a severe form of the disease. More...
22 Jul 2020
Image: The Immunogenomic Landscape of Hematological Malignancies (Photo courtesy of Helsinki University Hospital).

Immunogenomic Landscape of Hematological Malignancies Mapped

The reaction of the body's immune system against cancer can be thought of as a cycle. Cancer cells contain proteins that differ from proteins in other tissue. Their components, known as antigens, have to be presented to the T cells of the immune system by the cancer cells. More...
20 Jul 2020
Image: The Dimension Vista 500 Intelligent Laboratory System (Photo courtesy of Siemens Healthineers).

Clonal Hematopoiesis of Indeterminate Potential Associated with hsC-Reactive Protein

Clonal hematopoiesis (CH) occurring in normally aging subjects, initially suggested by X-chromosome inactivation studies, is caused by acquired mutations in genes recurrently mutated in hematological cancers, and in non-driver candidates. More...
14 Jul 2020
Image: A novel LSR-based coagulation sensor called iCoagLab has been favorably compared to thromboelastography to estimate bleeding risk (Photo courtesy of Massachusetts General Hospital).

Novel Device Compared to Thromboelastography for Clotting Defects

Clotting disorders occur when the body is unable to make sufficient amounts of the proteins that are needed to help the blood clot, stopping bleeding. These proteins are called clotting factors (coagulation factors). All clotting factors are made in the liver which requires vitamin K to make some of the clotting factors. More...
09 Jul 2020
Image: MACS cell separation kit uses a combination of superparamagnetic nano-sized beads and a very high magnetic gradient in MACS Columns (Photo courtesy of Miltenyi Biotec).

Diagnostic Assay Developed for Unclassified Severe Combined Immune Deficiency

Severe combined immune deficiency (SCID) is a group of rare hereditary genetic disorders, and is characterized by a total absence of immune system function, including an absence of T-lymphocytes, the white blood cells that play a crucial role in the body's immune defense. More...
30 Jun 2020
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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