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Molecular Diagnostics

Image: The Precursor-M+/QIAsure Methylation Test (Photo courtesy of Self-screen B.V.)

Molecular IVD Assay Identifies Women at High Risk for Cervical Cancer

A new molecular assay that has been demonstrated as a sensitive follow-up test to identify HPV positive women with progressing cervical disease in direct need for colposcopy or other follow-up procedures will help to identify women at high risk for cervical cancer. More...
12 Oct 2022
Image: A new tool could more quickly detect tick-borne diseases via blood sample on single chip (Photo courtesy of Pexels)

Rapid Diagnostic Tool to Revolutionize Diagnosis of Tick-Borne Diseases

A team of biomedical engineers is developing a tool that more quickly detects tick-borne diseases such as Lyme disease via a blood sample on a single chip. More...
11 Oct 2022
Image: AmplideX PCR/CE FMR1 Reagents are for the detection of CGG repeats in the fragile X mental retardation (FMR1) gene. These reagents provide a PCR-only approach based on Triplet Repeat Primed PCR (TP-PCR) design to reliably amplify and detect all alleles including Full Mutations (Photo courtesy of Asuragen)

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Fragile X syndrome (FXS), the most common form of inherited intellectual disability and monogenic cause of autism spectrum disorders, is mainly caused by the expansion of CGG trinucleotide repeats in the 5′ untranslated region of FMR1 gene. More...
10 Oct 2022
Image: Histopathology of a biopsy from a patient with Dilated Cardiomyopathy. The myocytes have lost myofibrils and empty spaces have appeared within the cytoplasm (Photo courtesy of Professor Michael John Davies, MD, FRCPath)

Genetic Prognosis Explored for Pediatric Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) in children is a disease in which, due to abnormalities in the muscle, one or both ventricles in a child’s heart become enlarged and contract poorly. A variety of processes that result in myocardial damage can lead to dilated cardiomyopathy and coronary artery disease. More...
10 Oct 2022
Image: Concept for digital detection of amyloid β-binding exosomes in blood of Alzheimer’s disease model mouse (Photo courtesy of Hokkaido University)

Highly Sensitive Biosensing Technology Diagnoses Alzheimer’s Disease in Blood

Scientists have developed a biosensing technology that can detect amyloid β (Aβ)-binding exosomes in the blood of mice, which increase as Aβ accumulates in the brain - one of the primary causes of Alzheimer’s disease. More...
10 Oct 2022
Image: Neuroblastoma circulating tumor cells (CTCs) expressing characteristic genetic biomarkers were isolated using cell size-based separation (Photo courtesy of Frontiers in Oncology (2022). DOI: 10.3389/fonc.2022.939460)

A Novel Gene Signature Predicts Likelihood of Neuroblastoma Relapse

Cancer researchers identified distinct circulating tumor cell and disseminated tumor cell gene expression signatures that distinguished neuroblastoma patients with bone marrow metastases at initial diagnosis, and that persisted in patients with subsequent relapse. More...
07 Oct 2022
Image: DiaSorin will develop, verify, and clinically validate the FDA- cleared and CLIA-waived LIAISON NES POC analyzer (Photo courtesy of DiaSorin)

State-Of-The-Art POC Molecular System to Allow Untrained Operators to Perform Testing for Viral and Bacterial Pathogens

DiaSorin (Saluggia, Italy) has announced that DiaSorin Molecular LLC will collaborate with the Biomedical Advanced Research and Development Authority (BARDA), to support the FDA 510(k) clearance of a CLIA-waived molecular solution for infectious disease testing. More...
07 Oct 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.