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Molecular Diagnostics

Image: UriFind is a urine-based, non-invasive molecular test for detection of bladder cancer (Photo courtesy of Pexels)

Urine-Based, Non-Invasive Molecular Test Accurately Detects Bladder Cancer

A new study aims to evaluate the performance of a non-invasive, quantitative real-time PCR (qPCR) assay designed to detect two DNA methylation biomarkers in urine specimens from patients suspected of having bladder cancer. More...
25 Nov 2022
Image: A micrograph showing cells with abnormal p53 expression (brown) in a brain tumor (Photo courtesy of Wikimedia Commons)

Altered Ratios of p53 Isoforms Predict Response of Breast Tumors to Chemotherapy

Alterations in the distribution of p53 isoforms are predictive of the likelihood that a breast tumor will respond to treatment with the chemotherapeutic drug doxorubicin. More...
24 Nov 2022
Image: PATHFAST is a compact immunoanalyzer with superior assay performance (Photo courtesy of PHC Europe)

Benchtop Immunoanalyzer Delivers Lab Quality Results for Cardiology, Intensive Care and Emergency Wards at POC

A compact immunoanalyzer with superior assay performance combines the accuracy of a full-scale lab analyzer with the flexibility of a mobile solution, making it an ideal analysis system for laboratories, hospitals and medical offices where fast quantitative results (with full-scale lab quality) are required at the point of care. More...
24 Nov 2022
Image: A blood test for people with high risk of breast cancer could diagnose the disease at early stage (Photo courtesy of Pexels)

Blood Test Could Screen for Changes in Proteins Prior to Breast Cancer Diagnosis

Researchers have found changes in the levels of particular proteins in people’s blood up to two years before they were diagnosed with breast cancer. The study could form the basis of blood testing for people with a genetic predisposition or a family history of breast cancer to ensure the disease is diagnosed early when the chances of survival are greatest. More...
23 Nov 2022
Image: TruSight Lymphoma 40 uses expert-defined content and proven next-generation sequencing (NGS) technology to identify somatic variants associated with lymphomas (Photo courtesy of Illumina)

Tumor Biopsies Analysis Performed on Newly-diagnosed B-cell Neoplasms

Comprehensive genomic analyses of tumor biopsies from patients with newly-diagnosed germinal center B cell (GCB) diffuse large B cell/high grade B cell lymphoma (DLBCL/HGBL) have identified molecular subtypes predictive of inferior survival, which are characterized by somatic mutations that can be detected through clinical laboratory mutation analysis (CLMA). More...
22 Nov 2022
Image: Mild versus severe immune response during COVID-19 infection (Photo courtesy of Wikimedia Commons)

Acute COVID-19 Infections Are Characterized by Elevated Blood Levels of IL-26

Increased systemic IL-26 was found to be associated with markers of hyperinflammation and tissue damage in patients with acute COVID-19, suggesting that it may be a potential target for diagnosis, monitoring, and therapy in this disease. More...
22 Nov 2022
Image: The developed micro-costing framework. cfDNA, cell-free DNA; ctDNA, circulating tumor DNA (Photo courtesy of the Amsterdam University Medical Centers)

New Tool Assesses Cost of ctDNA Testing

Circulating tumor DNA (ctDNA) is a promising new biomarker with multiple potential applications in cancer care. Estimating total cost of ctDNA testing is necessary for reimbursement and implementation, but challenging because of variations in workflow. More...
22 Nov 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.