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Molecular Diagnostics

Image: Screening for CMV throughout pregnancy is important to identify primary infections and to establish the timepoint of infection (Photo courtesy of EUROIMMUN)

Recombinant ELISAs Increase Efficiency of CMV Serodiagnosis in Pregnant Women

Cytomegalovirus (CMV) is a virus that is prevalent across the world and poses a significant risk during pregnancy due to vertical transmission to the fetus. Now, the findings of a new study could have significant practical relevance by reducing the laboratory workload and the costs involved in maternal CMV serodiagnostics. More...
20 Feb 2023
Image: The mass spectrometry-based test is designed for early detection of esophageal cancer (Photo courtesy of Pexels)

Novel Esophageal Cancer Test Could Reduce Unnecessary Endoscopies

Esophageal cancer is a highly lethal form of cancer, with an overall five-year survival rate of less than 20%. Now, a mass spectrometry-based test that, once clinically validated, could diagnose pre-cancerous cells years earlier than current standard diagnostic protocols for esophageal cancer, as well as reduce unnecessary endoscopies. More...
20 Feb 2023
Image: Higher concentration of α-synuclein aggregates in stool sample could be an indicator of early form of Parkinson’s (Photo courtesy of Pexels)

Non-Invasive Stool Test Could Diagnose Early Form of Parkinson’s Disease

In body-first Parkinson’s disease (PD), the characteristic deposits of aggregates of the body’s own α-synuclein protein are formed in the neurons in the intestine. Now, a research team has shown that a higher concentration of α-synuclein aggregates can be detected in the stool samples of PD patients. More...
17 Feb 2023
Image: MassARRAY benchtop system provides timely and accurate analysis of up to 1000s of samples in a single day (Photo courtesy of Agena Bioscience)

Benchtop Multiplex Genetic Analyzer Helps Target, Identify, and Confirm Clinically Relevant Mutations

Laboratories are required to maintain an efficient lab workflow in order to ensure the integrity of results. Now, a benchtop multiplex genetic analyzer empowers high-throughput testing by automating key aspects of sample preparation while providing laboratories with the flexibility to customize their extraction and sample preparation protocols. More...
17 Feb 2023
Image: A new tool could help scientists detect variants of viruses more quickly and easily (Photo courtesy of Pexels)

New Technique Designs Nucleic Acid Probes to Detect Rapidly Mutating Bacteria and Viruses

Researchers have developed a technique called AutoPLP that designs nucleic acid probes to help quickly, accurately and easily detect new variants of pathogens which can be hard to trace. This could help prevent infections that have the potential to spread quickly due to these dangerous variants. More...
16 Feb 2023
Image: Researchers have identified new molecules involved in diabetes (Photo courtesy of Pexels)

New Study to Help Identify Accurate microRNA Biomarkers for Early Detection and Treatment of Diabetes

Over the past two decades, researchers have conducted studies with animal or cell-based models which have suggested that specific small RNA molecules, called microRNAs, involved in controlling which genes are turned on and off in cells could help pancreatic islets develop and function normally. However, the specific role of these microRNAs in human pancreatic islets was poorly characterized. Now, a new large-scale genetic analysis has identified a set of microRNAs in pancreatic islets that are strongly associated with type 2 diabetes. More...
14 Feb 2023
Image: D-dimer can help in making the difficult diagnosis of prosthetic joint infection (Photo courtesy of Pexels)

D-Dimer Blood Test Detects Prosthetic Joint Infections as Accurately as Standard Tests

Plasma D-dimer, a test commonly used for certain blood clot-related disorders, is a potentially useful marker of infection and has been validated for use in the diagnosis of periprosthetic joint infection (PJI). However, some studies have raised concerns over the diagnostic performance of D-dimer testing for PJI, and its true accuracy is still unknown. Now, a new study suggests that the measurement of plasma D-dimer levels can provide useful information when making the difficult diagnosis of PJI. More...
13 Feb 2023
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.