Clinical Chemistry

Two Inflammatory Proteins Linked with Slower Cognitive Decline
Previous meta-analyses of case-control and prospective cohort studies showed that cytokines and inflammatory markers, such as interleukin-6 (IL-6), C-reactive protein (CRP), and others are elevated in Alzheimer's dementia cases and predicted incident of all-cause dementia. More...08 Jul 2021


FABP4 Concentrations Quantified in Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy (PDR), a progressive and serious stage of diabetic retinopathy (DR) due to retinal ischemia, is characterized by neovascularization (NV), vitreous hemorrhaging (VH) and tractional retinal detachment (TRD), all of which are major causes of blindness in patients with diabetes mellitus (DM). More...07 Jul 2021

Two Immunoassays Compared for Determination of Serum Vitamin D
Vitamin D is a fat-soluble steroid prohormone that is generated mainly in the skin by photochemical conversion of 7-dehydrocholesterol. 25-hydroxyvitamin D (25(OH)D) is its main storage form and is present in blood at very high concentration with respect to the active form 1,25-dihydroxyvitamin D. More...06 Jul 2021

Monocyte Distribution Width Evaluated as a Sepsis Indicator
Most current automated hematology analyzers have enhanced cell counting functions including the addition of new cell types such as nucleated red blood cells or immature granulocytes, making it possible to obtain a precise quantification of peripheral blood cells in pathological conditions. More...01 Jul 2021

Plasma Neurofilament Light Validated Biomarker for Neurological Conditions
In the management of neurological disorders, reliable and easily accessible biomarkers are needed to recognize or rule out an underlying neurodegenerative process contributing to cognitive decline at the earliest stage. More...30 Jun 2021

Diabetic Biomarkers Concordance Compared in South African Blacks
Sub-Saharan Africa is projected to experience a significant increase in the prevalence of diabetes mellitus by in the near future and accurate, comparable prevalence estimates will be essential to planning and monitoring by public health authorities. More...28 Jun 2021
In Other News
Plasma ACE2 Predicts Prognosis of COVID-19 Hospitalized Patients
Troponin Testing Presents Problems in Kidney-Impaired People
Hyperglycemia Evaluated as a Risk Factor in Pancreatic Cancer
Biomarker Predicts Crohn's Disease Relapse in Children
Serum Leptin Concentration Predict Cardiovascular Outcomes in Hemodialysis Patients
Urinary Sodium/Potassium Ratio Screens for Hyperaldosteronism in Hypertensive Men
Platelet Indices Analyzed for Tuberculosis and Diabetes Mellitus Co-Morbidity
Low-Density Lipoprotein Cholesterol Is Associated with Insulin Secretion
Serum Based Antigen Test Detects Childhood Tuberculosis
Low Sugar Metabolite Associated with Disability, Neurodegeneration in MS
Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma
Serum Catestatin Level Is Increased in Women with Preeclampsia
Plasma-Based S100B Testing for Management of Traumatic Brain Injury
Novel Diagnostic Test Assesses Risk of Urinary Uric Acid Crystallization
Maternal Multiomic Changes Could Predict Onset of Labor
Meconium Microbiome Can Help Predict Risk of Developing Allergies
Maternal Free Thyroxine Associated with Gestational Diabetes
ANGPTL8 Levels Associated with Hyperlipidemia in Primary Nephrotic Syndrome
Altered Perivascular Fibroblast Activity Precedes ALS Disease Onset
Blood-Based Markers Tied to Brain Cell and Memory Loss
Serum α-L-Fucosidase Activity Measured for COVID-19 Infection
Urinary Heat Shock Protein 70 Evaluated in Chronic Prostatitis
Breath Test Determines Severity of Methylmalonic Acidemia Disease
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.