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Clinical Chemistry

Image: The structure of the CEA125 protein. CEA125 has three domains: the N-terminal domain, tandem repeats domain and C-terminal domain. The N-terminal domain and tandem repeats are heavily glycosylated (Photo courtesy of Wikimedia Commons).

New Microarray-Based Glycoprofiling Test Diagnoses Ovarian Cancer

Cancer researchers have developed a microarray assay that identifies the abnormally glycosylated surface residues associated with ovarian tumor biomarker proteins such as CA125.  More...
27 Mar 2014
Image: Illumina HiSeq 2500 ultra-high-throughput sequencing system (Photo courtesy of Konrad Förstner).

New Gene Linked to Key Heart Attack Risk Factor

A previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks has been found.   More...
26 Mar 2014
Image: Ultra nano-liquid chromatography system (Photo courtesy of Eksigent).

Novel Candidate Protein Biomarkers Identified for Gastric Cancer

The early detection of stomach or gastric cancer has been revealed with the identification of four new biomarkers in the blood of human cancer patients.    More...
25 Mar 2014

Elevated Urinary Globotriaosylceramide Suggested as New Heart Disease Biomarker

Individuals with various forms of heart disease have been found to be a risk for a near term, potentially fatal cardiac event if they display high levels of urinary globotriaosylceramide.  More...
24 Mar 2014

New Blood-Test Evaluated to Identify Women at Risk for Ovarian Cancer

A team of researchers has discovered and verified a set of new blood-based biomarkers that distinguished between healthy woman and patients with ovarian cancer.  More...
23 Mar 2014
Image: The two new liquid assayed quality controls from Randox are supermix combinations of multiple controls for streamlining QC in clinical laboratories (Photo courtesy of Randox).

New Supermix Controls to Streamline QC in Clinical Laboratories

Two new liquid assayed chemistry controls have been designed to streamline quality control by cutting the number of individual QCs a laboratory needs to run in routine medical testing, saving time and money while ensuring highly accurate results and patient diagnosis.  More...
20 Mar 2014
Image: Photometric clinical tests for potassium, chloride, and sodium developed by DiaSys provide a reliable, cost-saving alternative or compliment to ISE-based measurement (Photo courtesy of DiaSys Diagnostics).

Photometric Tests for Common Electrolytes Provide High-Precision Alternative

As a high quality, reliable alternative or compliment to ion-selective electrode-based diagnosis, new photometric tests for sodium, potassium, and chloride provide accurate and precise results over a wide linear range, and are applicable to almost any clinical chemistry analyzer.  More...
19 Mar 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.