Clinical Chemistry
High-Sensitivity Troponin I Explored Post-Cardiac Surgery
Consensus recommendations regarding the threshold levels of cardiac troponin elevations for the definition of perioperative myocardial infarction and clinically important periprocedural myocardial injury in patients undergoing cardiac surgery range widely (from >10 times to ≥70 times the upper reference limit for the assay). Limited evidence is available to support these recommendations. More...07 Mar 2022
Repeatability and Reproducibility of a Handheld Quantitative G6PD Diagnostic
Novel treatment regimens for the radical cure of P. vivax malaria are more effective than current options but require prior quantitative G6PD testing. The reference method for quantitative G6PD measurement is spectrophotometry but, due to its operational characteristics, is not suitable for routine use. Furthermore, poor inter-laboratory reproducibility of spectrophotometry has prevented quantitative global definitions of G6PD deficiency. SD Biosensor (ROK) have developed a novel handheld “Biosensor” device (G6PD STANDARD), which measures G6PD activity within two minutes and has operational characteristics suited to point of care diagnosis. More...03 Mar 2022
Essential Amino Acids Associated With Complications in Liver Transplant Recipients
End stage liver disease is a major cause of morbidity and mortality worldwide and orthotopic liver transplantation (OLTx) is the only curative treatment. However, OLTx leads to its own risks and adverse sequelae. More...02 Mar 2022
Electrochemical Enzyme-Based Blood ATP and Lactate Sensor Monitors Disease Severity
Scientists have developed a prototype sensor that could help doctors rapidly measure adenosine triphosphate (ATP) and lactate levels in blood samples from patients, aiding in the rapid assessment of the severity of diseases. More...28 Feb 2022
Calprotectin Fecal Assay Adapted for Serum Samples
Calprotectin is a calcium-binding protein that can be measured in serum, plasma, and feces. Increased serum and plasma calprotectin concentrations have been found in chronic inflammatory rheumatic disorders. An analytical and clinical evaluation of the DiaSorin Liaison® fecal Calprotectin assay using LIAISON® XL was performed. More...16 Feb 2022
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ADAMTS-13 Protease Activity Test
ATS-13 Activity Assay
Anti-Cyclic Citrullinated Peptide Test
GPP-100 Anti-CCP Kit
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Automatic Western Blot Analyzer
Tenfly Phoenix Blot Analyzer
In Other News
Serum Glucose Identifies Hospitalized Stroke Patients at Greatest Risk for Recurrence
Blood Biomarkers May Distinguish Dementia Disorders
Simpler and Reliable ALS Diagnosis Enabled With Blood Tests
Genetic Clues Link Lipoprotein A to Prostate Cancer Risk
High NT-proBNP Paradoxically Shows Lower Risk in Early Pregnancy
New, Enzyme-Free Glucose Monitoring Sensor Solution Could Find Applications in Range of POC Diagnostics
ALT/AST Ratio Is an Independent Risk Factor for Gestational Diabetes Mellitus
Diagnostic Value of Serum CHI3L1 in Hepatocellular Carcinoma Explored
Proteomic Noninvasive Biomarkers Associated with Sport-Related Concussions
HOMA2-B Assessed for Type 1 Diabetes Risk
Fecal Immunochemical Test for Hemoglobin Evaluated on Automated System
Biochemical Parameters Compared for Diabetic Ketoacidosis Severity
Low Serotonin Levels Associated with Higher Nigral Iron in Parkinson’s Disease
Different Test Systems Analytical Performance Evaluated for Serum Creatinine
Blood Biomarker Kallikrein-8 Detects Amnestic Mild Cognitive Impairment
Nomograms Including Rapid Antigen Test Detects Primary Bladder Cancer
Near Normal Aminotransferase Levels Reported in Alcoholic Cirrhosis Patients
Serum High Sensitivity C-Reactive Protein Associated With Pre-Diabetes
Calprotectin Levels Vary When Measured in Different Matrices for COVID-19
Seasonal Temperature Impacts Patients’ Laboratory Results
D-Serine Clearance Evaluates Precise Measurement of Kidney Function
Long-Term Storage Stability of Corticotropin Investigated
Circulating ACE2 Activity Predicts Mortality and Severity in COVID-19 Patients
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.