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Clinical Chemistry

Image: The Phadia 250 Immunoassay Analyzer, in addition to allergy testing, allows measurement of autoantibodies of more than 20 autoimmune related diseases using the EliA product line (Photo courtesy of Thermo Fisher Scientific)

Biochemical Abnormalities Among Celiac Disease Patients Referred for Antibody Testing

Celiac disease (CD) is a chronic disease occurring in all age groups and affecting approximately 1% of the population, although many cases of CD remain undiagnosed. This condition is caused by an abnormal immune response in genetically susceptible individuals triggered by the ingestion of gluten proteins from wheat, rye and barley. More...
09 May 2022
Image: Smart diaper is designed for bedside urine testing (Photo courtesy of Unsplash)

Smart Diaper Could Provide Quick and Painless Bedside Urinalysis

Researchers have designed a flexible sensor that fits in a diaper, measures multiple components in urine and can share those results over Bluetooth to provide real-time bedside analyses for incontinent, elderly or infant patients. More...
06 May 2022
Image: N-terminal pro-B-type natriuretic peptides (NT-proBNP) concentration could mean drastically different absolute risks of heart failure (HF) for different demographics (Photo courtesy of TCTMD)

NT-proBNP Underestimates Heart Failure Risk for Certain Patients

The N-terminal pro-B-type natriuretic peptides (NT-proBNP) concentration could mean drastically different absolute risks of heart failure (HF) for different demographics, according to a cohort study suggesting the importance of sex and race in interpreting risk for people free of HF at baseline. More...
03 May 2022
Image: Study demonstrates significant inconsistencies with pediatric reference interval (Photo courtesy of Unsplash)

Groundbreaking Study Points to Crucial Gap in Children’s Clinical Testing

A groundbreaking study has demonstrated significant inconsistencies with pediatric reference intervals, which are essential to high quality pediatric medical testing. More...
03 May 2022
Image: Nanotechnology-enabled low-cost, POC test detects sodium (Photo courtesy of Pexels)

Paper-Based Sensor Strip Rapidly Detects Sodium in Urine and Blood at POC

A team of researchers has developed nanotechnology-based paper sensor strips to detect sodium focus in urine and blood serum that could revolutionize scientific analysis. More...
29 Apr 2022
Image: The Randox Lipoprotein(a), (Lp(a)), assay offers a truly accurate method for the assessment of Lp(a) in serum or plasma (Photo courtesy of Randox Laboratories)

Elevated Lipoprotein(a) Mediates Risk of Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults, with a prevalence between 0.5% and 2%. Longer life span and higher prevalence of AF risk factors are projected to further increase the global prevalence of AF. More...
27 Apr 2022
Image: Randox Daytona RX chemical analyzer (Photo courtesy of Gemini BV)

Urine Testing Differentiates Glomerular from Tubulointerstitial Diseases on Kidney Biopsy

Histological examination of kidney biopsy tissue can help differentiate between glomerular and tubulointerstitial diseases, as well as differentiate between their underlying etiologies and subtypes. More...
22 Apr 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.