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Clinical Chemistry

Image: A histopathology of a meningioma with brain invasion (WHO Grade II); the tumor (bottom/right of image) has the typical \"pushing border\" invasion into the cerebral cortex (Photo courtesy of Nephron).

High Blood Sugar Associated with Lower Risk of Benign Tumors

Meningioma, is a primary tumor arising from the membrane surrounding the brain and spinal cord, accounts for more than one-third of all primary brain and central nervous system tumors. More...
07 Jul 2016
Image: Professor Michael Wheeler with Ashley St. Pierre of the Hospital for Sick Children, conducting additional tests in women with gestational diabetes to evaluate racial and ethnic differences in prediction, and investigate high-risk groups with prediabetes to learn if metabolomics will predict type 2 diabetes in the general population (Photo courtesy of the University of Toronto).

Highly Accurate Method Developed Predicts Postpartum Diabetes

Gestational diabetes is defined as glucose intolerance that is first identified during pregnancy and it occurs in 3% to 13% of all pregnant women, and increases a woman's risk of developing type 2 diabetes by 20% to 50% percent within five years after pregnancy. More...
06 Jul 2016
Image: The Elecsys 2010 immunology analyzer (Photo courtesy of Roche Diagnostics).

Cardiac Biomarker Increase Associated with Higher Risk of Heart Disease

High-sensitivity cardiac troponin T (hs-cTnT), a protein that can be measured via a blood test, is a biomarker of cardiovascular risk and cardiac troponin is critical to the clinical diagnosis of heart attack, particularly among symptomatic persons with chest pain. More...
30 Jun 2016
Image: The enzyme immunoassay for quantitative determination of testosterone concentration in human serum (Photo courtesy of Pointe Scientific).

Testosterone Reference Ranges Vary Widely in Medical Laboratories

The evaluation and management of male hypogonadism should be based on symptoms and on serum testosterone levels and diagnostically this relies on accurate testing and reference values. This circumstance not only affects how clinicians determine treatment, but also whether insurers approve therapy for men with low testosterone levels. More...
30 Jun 2016
Image: The ADVIA 1800 clinical chemistry system (Photo courtesy of Siemens Healthcare).

Reproducibility Of Stored Serum Potassium Values Analyzed

The reproducibility of serum potassium values in serum from blood samples stored for increasing times prior to centrifugation and analysis has been investigated. More...
29 Jun 2016
Image: A photomicrograph of (#1) a round cell in urine sediment Sternheimer stain; (#2) a hyaline cast; (#3) and a macrophage (Photo courtesy of the University of Tokyo).

Urinary Round Cells Predict Need For Hemodialysis

Urinalysis is a safe, easy, and cost-effective diagnostic tool, and sediments are indicative of nephron condition, therefore, it can be considered as a virtual renal biopsy and is useful for the differential diagnosis of acute kidney injury and chronic kidney disease. More...
28 Jun 2016
Image: The QP2010 Plus gas chromatography-mass spectrometry analyzer (Photo courtesy of Shimadzu).

Breath Analysis Aims To Reduce Unnecessary Antibiotic Prescriptions

A number of multiresistant pathogens including Acinetobacter baumannii place a heavy burden on ventilator-associated pneumonia (VAP) patients in intensive care units (ICU), and it is critically important to differentiate between bacterial infection and colonization to avoid prescribing unnecessary antibiotics. More...
23 Jun 2016
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.