Clinical Chemistry

Analytical Performance of Novel Glycated Albumin Assay Evaluated
Diabetes is a complex, chronic illness requiring continuous medical care with multifactorial risk-reduction strategies beyond glycemic control. Hemoglobin A1c (HbA1c) reflects the concentration of mean plasma glucose (MPG) over the last 2–3 months and has been the gold standard for monitoring glycemic control of diabetic patients in clinical practice. More...26 May 2022

Different Subtypes Defined In Small Cell Lung Cancer
Small cell lung cancer (SCLC) is a malignant disease associated with a particularly high mortality rate. SCLC is a particularly aggressive cancer that typically occurs in smokers, exhibiting rapid growth and a high propensity for metastasis. More...25 May 2022

Potential Biomarker Found for Sudden Infant Death Syndrome
The term Sudden Unexpected Death in Infancy (SUDI) covers both explained and unexplained deaths. The unexplained deaths are termed Sudden Infant Death Syndrome (SIDS). Despite intensive studies over the past decades, the mechanisms which lead to SIDS remain elusive. More...23 May 2022

Complete Blood Count Parameters Associated With Pancreatic Beta-Cell Function
The pathophysiology of type 2 diabetes mellitus (T2DM) involves insulin resistance (IR) and progressive deterioration of beta-cell function (BCF). Estimation of IR and BCF is essential for screening subjects at a high risk of T2DM and making treatment plans in clinical practice. More...19 May 2022

Lipid Measurements Show Potential as Alzheimer’s Disease Biomarkers
Brain changes accompanying ageing are varied and can include pathologies that lead to cognitive impairment, the commonest of which is Alzheimer’s disease (AD). Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. More...17 May 2022

Mindray Launches High Throughput BS-600M Chemistry Analyzer with Industry-Leading Small Footprint
Mindray (Shenzhen, China) has launched the new BS-600M, a powerful yet efficient chemistry analyzer designed to empower medium-volume laboratories with increased productivity, efficiency and reliability. More...16 May 2022

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury
Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...12 May 2022
In Other News
Tear-Based Method Detects Breast Cancer
Proteins Linked to COVID-19-Associated Inflammatory Syndromes
Biochemical Abnormalities Among Celiac Disease Patients Referred for Antibody Testing
Smart Diaper Could Provide Quick and Painless Bedside Urinalysis
NT-proBNP Underestimates Heart Failure Risk for Certain Patients
Groundbreaking Study Points to Crucial Gap in Children’s Clinical Testing
Paper-Based Sensor Strip Rapidly Detects Sodium in Urine and Blood at POC
Elevated Lipoprotein(a) Mediates Risk of Atrial Fibrillation
Urine Testing Differentiates Glomerular from Tubulointerstitial Diseases on Kidney Biopsy
Lipidomics Approach Developed to Predict Cardiovascular Disease, Diabetes
Sex Hormones Influence HbA1c Levels in Non-Diabetic Population
Proteomic Blood Test Predicts Cardiovascular Risk
Urine Sediment Findings in Patients With COVID-19-Associated Renal Injuries
Diabetic Kidney Disease and Risk of Incident Stroke Among T2D Adults
Serum Antinuclear Antibody Correlated in Hispanic Pediatric Patients With NFLD
Pre-Analytical Stability of Serum Biomarkers for Neurological Disease Investigated
Midlife Lipid and Glucose Levels Are Associated With Alzheimer's Disease
Albumin-Related Ratios Investigated in HBV-Associated Decompensated Cirrhosis
Biomarkers Associated With Cardiovascular Outcomes in Psoriatic Patients
Serum Folate Deficiency in Older People Associated With Heightened Dementia
Serum Extracellular Vesicle Arginase 1 Measured In T2DM
Biosensors Use Non-Invasive Urinalysis and AI for Quick Assessment of Cancer Treatment
Proline-Specific Peptidase Activities in Plasma of Hospitalized COVID-19 Patients
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.