Clinical Chemistry
New Defined Reference Range for Testosterone Levels Established
Through a landmark study based on cohorts in the USA and Europe, researchers have established a harmonized reference range for testosterone levels in men to help limit misdiagnoses and unnecessary treatments. This can be particularly helpful in identifying patients with hypogonadism, as the lack of both defined reference ranges of testosterone and of standardization of hormone assays has made diagnosing hypogonadism a difficult task. More...24 Jan 2017
Novel Biosensor Selectively Measures Cancer Patient p53 Autoantibodies
A team of Spanish cancer researchers has developed a disposable electrochemical biosensor for the specific and sensitive determination of p53-specific autoantibodies, which are biomarkers for certain types of cancers with p53 gene mutations. More...24 Jan 2017
Comparison of Vitamin Concentrations in Tears and Serum
Results obtained during a recent study suggest that tears could be used as specimens to monitor nutritional health, since they are easily obtained, sufficiently mirror blood serum data, and enhance the speed of deficiency diagnoses. More...24 Jan 2017
Blood Test Predicts Silent Heart Disease Risk
Coronary heart disease is the UK's single biggest killer, accounting for nearly 70,000 deaths in the UK each year. When heart muscle is damaged it leaks a protein called troponin in to the blood stream. Patients suspected of suffering a heart attack will often be given a troponin test to aide diagnosis, but until now the test has not been used to assess future heart attack risk. More...19 Jan 2017
Early Biomarker Found for Sepsis-Induced Kidney Injury
Sepsis is a worldwide health care problem and a leading cause of death of patients in intensive care unit. On the other hand, acute kidney injury (AKI) is a clinical syndrome of an abrupt renal dysfunction leading to uremic toxins accumulation and several organs dysfunction. More...19 Jan 2017
Dysbiosis of Urinary Microbiota Positively Correlated with Diabetes
Type 2 diabetes mellitus (T2DM) accounts for 90% of diabetes, and T2DM is not due to insufficient use of insulin but due to insufficient insulin secretion and insufficient insulin action. Hospitalization rate for urinary tract infection (UTI) caused by diabetes is over twice as much as those caused by other factors. More...19 Jan 2017
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In Other News
Combined Urinary Procedure Used to Diagnosis Mucopolysaccharidoses
New Diagnostic Tests Improve Care for Heart Failure Patients
Biomarker Signatures Predict Aging Health Quality
Nanoarray Senses and Distinguishes Multiple Diseases
New Automated Periostin Immunoassay Developed
Iron Deficiency Anemia Associated with Hearing Loss
Multiple Sclerosis Associated with Leaked Hemoglobin in Brain
Blood Test Predicts How Long Cancer Patients Will Survive
Kidney Biomarkers Investigated to Track Lupus
Early Signs of Alzheimer's Detected in Cerebrospinal Fluid
Inflammatory Markers Predict Risk of Morbidity and Mortality
Change in Serum Bilirubin Level Predicts Incident Metabolic Syndrome
Performance of Second Generation Cortisol Assay Evaluated
Lower Cut-Off Point of Blood Glucose May Define Prediabetes
Hand-Held Blood Analyzer Receives CE Mark
Neonatal Vitamin D Level Predict Multiple Sclerosis Risk
Combination of Tests Enhances Urinary Tract Infection Localization
Point-of-Care System Evaluated for Measuring Cardiac Troponin I
Plasma NT-ProBNP Levels Predict Severity of Enterovirus-71 Infection
Routine Lab Tests May Help Diagnose Cachexia in Cancer Patients
Peptide Serum Markers Predict Type 1 Diabetes
Hypoglycemia in Hospitalized Patients Linked to Increased Mortality Risk
Simple Saliva Test May Help Diagnose Kidney Disease
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.