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Clinical Chemistry

Image: The ABI-Prism 3500 genetic analyzer (Photo courtesy of Applied Biosystems).

Lab Evidence Confirms Outbreak of Haff Disease

Haff disease is a syndrome of unexplained rhabdomyolysis following consumption of certain types of fish, and it is caused by an unidentified toxin. Rhabdomyolysis is a clinical syndrome caused by injury to skeletal muscle that results in release of muscle cell contents into the circulation. More...
28 Jun 2017
Image: The Gentian NGAL Immunoassay is a new particle-enhanced turbidimetric immunoassay (PETIA) for in vitro diagnostic testing of neutrophil gelatinase-associated lipocalin (NGAL) in human urine and plasma samples (Photo courtesy of Gentian).

Enhanced Immunoassay Validated for NGAL

The ectopic expression of Neutrophil Gelatinase-Associated Lipocalin (NGAL) has been reported in patients with various malignancies such as kidney, colorectal, gastric, pancreatobiliary, hepatic, breast, gynecological and hematologic cancers. More...
28 Jun 2017

Cholesterol Test May Help Assess Heart Disease Risk

Researchers have developed a first-of-its-kind rapid assay for measuring effectiveness of a patient’s high-density lipoprotein cholesterol (HDL-C) in cleaning up arterial cholesterol. This HDL-C function test could improve risk assessment and diagnosis, and help provide and monitor more personalized treatments for cardiovascular disease (CVD) patients. More...
27 Jun 2017
Image: An illustration of Coll2-1, a marker specific of type II collagen degradation in osteoarthritis (Photo courtesy of Artialis).

Specific Biomarker Assessed for Cartilage Degradation

Osteoarthritis (OA) is one of the most common forms of musculoskeletal disorders and one of the major causes of pain and disability in the adult population. Viscosupplementation is a symptomatic treatment of the knee osteoarthritis based on the intra-articular injection of hyaluronic acid (IAHA). More...
21 Jun 2017

Pre-Op Cholesterol Level Predicts RCC Patients Survival

Renal cell carcinoma (RCC) is the most frequently diagnosed renal malignancy. The constant advances of modern imaging technologies and the percentage of incidentally detected renal tumors has constantly increased during the last couple of decades, and a good percentage of patients are still diagnosed with metastatic renal cell carcinoma (mRCC). More...
21 Jun 2017
Image: The Quo-Test HbA1c fully automated analyzer uses patented boronate fluorescence quenching technology to measure glycated hemoglobin from a 4 μL sample taken from a finger prick or venous whole blood (Photo courtesy of EKF Diagnostics).

POC Analyzer Compared with HPLC Method

The measurement of the glycated fraction of hemoglobin (HbA1c) has been recommended to diagnose diabetes, in addition to monitoring glycemic control. HbA1c reflects long-term glycemic control over the preceding two to three months as opposed to glycemic control at a single point in time. More...
20 Jun 2017
Image: The Videssa Breast protein biomarker blood test for breast cancer evaluates 11 serum protein biomarkers and 33 tumor-associated autoantibodies (Photo courtesy of Provista Diagnostics).

Blood Test Offers Improved Breast Cancer Detection

Breast cancer is predicted to be the second leading cause of cancer deaths in the USA women. Approximately 232,000 cases of invasive breast cancer and 60,000 cases of ductal carcinoma in situ (DCIS) are diagnosed and 40,000 deaths occur annually. More...
16 Jun 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.