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Clinical Chemistry

Image: One drop of blood is enough for TBIcheck to diagnose a possible mild brain trauma. If a line appears below the control line, the injured person will have to go to the hospital for a CT scan (Photo courtesy of the University of Geneva).

Mild Brain Trauma Diagnosed with POC Device

Every year in Europe, three million people are admitted into hospitals for suspected mild traumatic brain injury (mTBI) cases. Biomarkers have been intensively studied for their potential as diagnostic tools in cases of mTBI to allow accurate diagnosis, improve patient management speeds and reduce medical costs. More...
14 Aug 2018
Image: The Brain Trauma Indicator kit that measures the biomarkers, Ubiquitin Carboxy-terminal Hydrolase-L1 (UCH-L1) and Glial Fibrillary Acidic Protein (GFAP) (Photo courtesy of Banyan Biomarkers).

Blood Biomarker Indicates Extent of Traumatic Brain Injury

An estimated 54 million to 60 million people worldwide sustain a traumatic brain injury (TBI) annually. In the USA, more than 2.5 million people are diagnosed with TBI each year and most of those are from concussions. More...
10 Aug 2018
Image: A photomicrograph of squamous-cell carcinoma, a type of non-small-cell carcinoma of the lung, from a fine needle aspiration specimen (Photo courtesy of Nephron).

Cancer Risk Assessed by Circulating Protein Biomarker Panel

The question has been asked whether a risk prediction model based on circulating protein biomarkers improve on a traditional risk prediction model for lung cancer and the current USA screening criteria. More...
10 Aug 2018
Image: An ELISA for quantitative determination of leptin in human serum and plasma (Photo courtesy of Diagnostic Automation).

Leptin to Adiponectin Ratio Predicts Metabolic Function in Obesity

There is an epidemic of obesity and the metabolic syndrome in the USA and across the world. Both entities are associated with high mortality, mainly as a result of cardiovascular disease. The epidemic of obesity has been paralleled by an increase in the incidence of chronic kidney disease. More...
08 Aug 2018
Image: Postmenopausal factors may have an impact on the heart-protective qualities of high-density lipoproteins (HDL), also known as ‘good cholesterol (Photo courtesy of University of Pittsburgh Medical Center).

HDL Does Not Always Lower Risk of CV Disease

High-density lipoproteins (HDL) are a family of particles found in the blood that vary in sizes and cholesterol contents. HDL has traditionally been measured as the total cholesterol carried by the HDL particles, known as HDL cholesterol. More...
02 Aug 2018
Image: The Dionex Ultimate 3000 UHPLC system coupled with the high-resolution nano-ESI Orbitrap-Elite mass spectrometer (Photo courtesy of Thermo Fisher Scientific).

Saliva Test Could Improve Diabetes Control and Treatment

People with type 1 diabetes do not produce enough insulin. The hormone insulin is required for the body to use sugar for energy, so lack of insulin causes unused sugar to accumulate in the blood. This excess sugar in turn leads to complications like cardiovascular, kidney, eye and nerve damage. More...
31 Jul 2018
Image: The Giraffe Blue PT Lite Phototherapy system (Photo courtesy of GE Healthcare).

Transcutaneous Bilirubin Estimated in ELBW Infants

Hyperbilirubinemia is seen in almost two-thirds of term and more than two-thirds of all preterm infants. The incidence of kernicterus has dramatically decreased since the onset of regular screening and aggressive management with phototherapy (PHT). More...
31 Jul 2018
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.