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Clinical Chemistry

Image: The bile acid blood test is used to predict stillbirth risk (Photo courtesy of bluehorizon).

Simple Bile Acid Blood Test Predicts Stillbirth Risk

Intrahepatic cholestasis of pregnancy (ICP) is caused by a build-up of bile acids in the blood, and symptoms include pruritus. ICP is a liver disorder affecting approximately 5,300 pregnancies annually in the UK, more than 14 every day. More...
25 Feb 2019
Image: The JCA-BM8000 automatic analyzer series (Photo courtesy of JEOL).

HDL Cholesterol Measurement Unaffected by Serum Amyloid A

High-density lipoprotein cholesterol (HDL) is known as the anti-atherogenic lipoprotein. Epidemiological studies have shown that low plasma concentrations of HDL are associated with an increased risk of cardiovascular events. More...
25 Feb 2019
Image: Halosperm is an in vitro diagnostic kit that allows the measurement of DNA fragmentation in a fast, easy, and reproducible manner, without the need for complex laboratory equipment (Photo courtesy of Halotech DNA SL).

Markers in Male Reproductive Impairments Causing Miscarriages

Recurrent pregnancy loss, (RPL) affecting 1% to 2% of couples, is defined as ≥3 consecutive pregnancy losses before 20-week' gestation. Women with RPL are routinely screened for etiological factors, but routine screening of male partners is not currently recommended. More...
21 Feb 2019
Image: Clusterin can accumulate in juxtanuclear aggregates. Clusterin is a chaperone protein that is synthesized in response to cellular stress. It often appears in cells undergoing apoptosis and is linked to an increased risk for heart disease (Photo courtesy of The Company of Biologists).

Protein Linked to Increased Risk for CVD and Stroke

The overproduction of the protein clusterin can cause cardiometabolic syndrome, which is a combination of high blood pressure, high blood sugar, and extra body fat around the waist and high cholesterol or triglyceride levels. More...
20 Feb 2019
Image: The Wyn-CE Adaptive Capillary Electrophoresis system and ER815 C4D Detector (Photo courtesy of WynSep).

Sweat Chloride Quantified Using Capillary Electrophoresis

Cystic fibrosis (CF) is the less rare and severe genetic disease among the European population. Biochemical diagnosis of CF is based on the demonstration of increased chloride concentration in sweat samples, obtained during the sweat test (ST). More...
18 Feb 2019
Image: The Saliva Glucose Biosensor that measures glucose in saliva rather than blood (Photo courtesy of iQ Group Global).

New Glucose Biosensor Introduced for Diabetes Management

The world’s first saliva-based glucose test for diabetes management that measures glucose in saliva rather than blood has been introduced. More...
11 Feb 2019
Image: The Olympus AU680 automated analyzer (Photo courtesy of Beckman Coulter).

HDL Subclasses Linked to Mortality in Heart Failure Patients

Heart failure (HF) is a frequent cause of morbidity and mortality worldwide and is defined by the as an abnormality of the cardiac structure and function, resulting in a diminished ability of the heart to maintain optimal perfusion of metabolizing tissues. More...
11 Feb 2019
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.