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Clinical Chemistry

Image: Rapid breath analysis for acute respiratory distress syndrome diagnostics using a portable two-dimensional gas chromatography device (Photo courtesy of University of Michigan).

Portable Monitor Detects Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome (ARDS) is the most severe form of acute lung injury, responsible for high mortality and long-term morbidity. As a dynamic syndrome with multiple etiologies, its timely diagnosis is difficult as is tracking the course of the syndrome. More...
22 Aug 2019
Image: A new study showed men with diabetes had a higher blood testosterone level than non-diabetic men (Photo courtesy of Diamed Diagnostical Center).

Hormone Levels of Diabetic Men Not Related to Prostate Cancer Risk

Diabetes mellitus (DM) is a group of metabolic disorders characterized by high blood sugar levels over a prolonged period and is conventionally associated with an increased risk of cancer; however, inverse associations of diabetes with prostate cancer are well described. More...
21 Aug 2019
Image: The Architect 25-OH Vitamin D reagent kit (Photo courtesy of Abbott).

Two Vitamin D Immunoassays Compared

Vitamin D can be synthesized in skin from 7-dehydrocholesterol following ultraviolet light exposure, which produces Vitamin D3 (cholecalciferol). Vitamin D2 (ergocalciferol) is present in plant sources, and can be absorbed from the diet. More...
20 Aug 2019
Image: A histopathology of pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer, arising in the pancreas head region (Photo courtesy of KGH).

Pancreatic Cancer Risk Rises with Fasting Glucose

More than 56,000 Americans are expected to be diagnosed with pancreatic cancer in 2019, which is more than 150 people diagnosed every day. Pancreatic cancer is the ninth most commonly diagnosed cancer in women and the 10th most commonly diagnosed in men in the USA. More...
15 Aug 2019
Image: The GeneXpert MTB/RIF assay is designed as a rapid diagnosis test of Tuberculosis (TB) and drug resistance (Photo courtesy of Cepheid).

Serum Siderocalin Measured in Patients with TB and HIV

Tuberculosis (TB) continues to be a significant cause of morbidity and mortality worldwide. The progression from uninfected or latently infected to active TB is often insidious and has minimal symptoms in the initial months, resulting in delayed diagnosis and poor outcomes. More...
14 Aug 2019
Image: The Xevo TQ-S micro Triple Quadrupole Mass Spectrometry (Photo courtesy of Waters).

High Fetal Estrogen Levels Linked to Autism

The male-biased prevalence of autism, together with the finding that autistic girls have a higher mutational load than autistic boys, suggests that males have a higher likelihood of developing autism. More...
13 Aug 2019
Image: Scientists determined that one-third of total cholesterol in plasma was present in remnant lipoproteins, which is in the triglyceride-rich lipoproteins intermediate-density lipoprotein (IDL) and very low-density lipoprotein (VLDL) (Photo courtesy of Harvard Medical School).

High Remnant Particle Cholesterol Levels Profiled in Blood

Three quarters of the Danish population have moderately elevated levels of cholesterol. If cholesterol levels are too high, risk of cardiovascular disease is increased. Often, low-density lipoprotein (LDL) cholesterol, the so-called bad cholesterol, is considered the culprit. More...
13 Aug 2019
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.