Clinical Chemistry

Hematological Parameters Evaluated for Cervicocranial Arterial Dissection Stroke
As artery detachment, artery dissection refers to the vascular disease in which blood flow enters the artery wall and causes dissection of vascular wall. Cervicocranial arterial dissection (CCAD) can lead to stenosis or occlusion of the lumen has become one of the most frequent causes for ischemic stroke in the young. More...23 Sep 2020

Complex ABO Glycan Phenotypes Predicted by Lectin Microarrays
Serological classification of individuals as A, B, O, or AB is a mainstay of blood banking. ABO blood groups or ABH antigens, in addition to other surface glycans, act as unique red blood cell (RBC) signatures and direct immune responses. ABO subgroups present as weakened, mixed field, or unexpected reactivity with serological reagents, but specific designations remain complex. More...16 Sep 2020

Novel Blood Test Predicts Psychotic Disorders Before They Emerge
Only around a quarter of young people who display mild, transitory psychotic symptoms at an early age ultimately go on to develop a serious psychotic disorder. Schizophrenia, for example, is generally not clinically diagnosed until a person reaches their twenties. More...15 Sep 2020

Equivocal HbA1c Test Results Increases Risk of Neonatal Hypoglycemia
Maternal diabetes, including gestational diabetes, typically diagnosed by an oral glucose tolerance test in the second trimester, is a known risk factor for neonatal hypoglycemia and infants born large for gestational age. More...10 Sep 2020

Diabetes Blood Markers Linked to Alzheimer’s Disease Pathology
Alzheimer's is a progressive disease, where dementia symptoms gradually worsen over a number of years. In its early stages, memory loss is mild, but late-stage Alzheimer's, individuals lose the ability to carry on a conversation and respond to their environment. More...09 Sep 2020

Plasma Eicosanoids Characterized During Gestation Predicts Outcome
Fetal growth disorders are major risk factors for adverse pregnancy and later life outcomes. Proxy outcomes for disorders of fetal growth include small for gestational age (SGA) and large for gestational age (LGA) birth weight. Risk factors for SGA include maternal obstetrical complications, fetal genetic factors, infection, and various medical conditions. More...03 Sep 2020

Lymphocyte Count Correlated to Comorbid Diabetes and COVID-19
The coronavirus disease (COVID-19) that erupted in China since December 2019 and has gradually spread throughout the world. At present, it has caused tens of thousands of deaths, and the efficacy of certain antiviral drugs is still under review. More...03 Sep 2020
In Other News
Biomarkers Evaluated for Severity of Diabetic Kidney Disease
Nanoparticle System Captures Heart-Disease Biomarker From Blood
High Blood Glucose Tied to Cardiovascular Risk in Diabetes
New Technique Predicts Preterm Births in High Risk Women
Dolichol Biomarker Evaluated for Congenital Disorders of Glycosylation
Simple Urine Test Significantly Improves Detection of Adrenal Cancer
Lipocalin 2 Proposed as Biomarker for Bacterial Meningitis
Protracted Ketonemia Reported in Hyperglycemic COVID-19 Emergencies
Plasma Lipidome Investigated in Hereditary Hemochromatosis
Different Ways of Measuring HDL Predicts Cardiovascular Disease
Melatonin Levels in Parkinson’s Patients Linked to Non-Motor Symptoms
Blood Tests Predicts the Risk of Liver Cirrhosis
Fully-Automated Calprotectin Immunoassay Validated for IBD Patients
Geochemistry Test Identifies Osteoporosis Earlier Than Standard Method
Pediatric CKD Progression Linked to Low Serum Bicarbonate
Presepsin Values Evaluated as Sepsis Severity Markers
Pregnancy TSH Variations Prompt Erroneous Thyroid Disease Diagnosis
Biomarkers Evaluated for Lung Disease Severity in Cystic Fibrosis
Metabolite Profiling Reveals Predictive Biomarkers for Amyotrophic Lateral Sclerosis
Serum Free Thiols Predict Cardiovascular Events
Urine Testing Method Developed for Ureterolithiasis
Glucose Levels Linked to Maternal Mortality Even in Non-Diabetic Women
Endogenous Testosterone Levels Associated with Risk of Diabetes
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.