Clinical Chemistry

Smartphone-Based Readerless System Measures Blood Glucose for Early Detection of Prediabetes
Screening for prediabetes typically involves laboratory testing at a healthcare facility or using a portable glucometer for at-home testing. Unfortunately, access and cost may limit widespread screening. Now, researchers have discovered an optimal approach to enhance early detection of prediabetes. More...
03 Apr 2023

Rapid, Non-Invasive Method Diagnoses Type 2 Diabetes by Sniffing Urinary Acetone
A research team working on a new non-invasive screening method for Type 2 diabetes (T2D) has used self-developed proton transfer reaction-mass spectrometry (PTR-MS) to detect volatile organic compounds (VOCs) in T2D patients' urine samples. More...22 Mar 2023

Urine Test Accurately Predicts End of Life for Lung Cancer Patients
A new study has found that lung cancer patients can have their risk of mortality accurately predicted within the last four weeks of life by analyzing their urine. This information gives both the patient and their families the chance to prepare for the end of life, while also providing clinicians with more detailed data to inform their care and medication plans. More...01 Mar 2023

Blood Test Identifies Prediabetics with Highest Risk of Developing Diabetes Before Symptoms Develop
A blood test can identify high-risk, asymptomatic patients with prediabetes who cannot be detected by standard diabetes tests, hemoglobin A1C and glucose. The test meets a critical clinical need as it can be used by physicians to identify patients closest to developing type 2 diabetes and provide treatment to prevent the onset of the disease. More...
27 Feb 2023

Wearable Sensing Patch Enables Rapid Quantitative Analysis of Urea in Body Fluids
There has been growing focus on wearable fluorescence-based sensors, although traditional fluorescent hydrogels are excited by short wavelengths, hampering the detection of biological samples. Now, researchers have developed a wearable sensing patch that enables the rapid quantitative analysis of urea. More...24 Feb 2023

Strip-Type Urine Sensor Diagnoses Cancer Quickly and With High Sensitivity
Various blood tests, radiological methods and histological analysis are currently used to diagnose cancer. Annual health checkups can also reveal the presence of cancer, although the disease is mostly detected after it has advanced considerably, resulting in delayed treatment or death. Now, a research team has developed a strip-type urine sensor that can amplify the light signal of metabolites in urine to help diagnose cancer. More...15 Feb 2023

Carolina Liquid Chemistries and Diazyme Enter Into Partnership
Carolina Liquid Chemistries, Corp. (CLC, Greensboro, NC, USA) and Diazyme Laboratories, Inc. (San Diego, CA, USA) have entered into a partnership to expand the test menu on the Diazyme DZ-Lite c270 benchtop clinical chemistry analyzer, allowing it to run both special and routine chemistries. More...24 Jan 2023
In Other News
Smart Fibers Could Allow T-Shirts to Analyze Electrolytes and Metabolites in Sweat
Revolutionary Transistor Could Allow Wearable Devices to Measure Sodium and Potassium in Blood
Liquid-Ready QC Solution for POC Urinalysis Instruments Helps Labs Streamline Daily Operations
Urinary NAG-Creatine Ratio Predicts Advanced Diabetic Kidney Disease
Impact of Preanalytical Factors on Calprotectin Concentration in Stool
Biomarkers Associated With Immune Checkpoint Inhibitor Myocarditis Revealed
Anti-Müllerian Hormone Linked to Lipid Levels in Midlife Women
Simple Blood Test Can Detect Predictive Biomarker for Cognitive Impairment and Dementia
CSF Glucose Unaltered in Patients With Dementia
Ground-Breaking New Method for Multi-Cancer Early Detection Is More Practical and Cheaper
CHI3L1 Protein Differentially Expressed in Appendicitis and Appendix Carcinomas
Biomarker-Based Blood Test Assesses Risk for Diabetic Kidney Disease Before Symptoms Appear
First-Ever Urine Biomarker Test Could Reveal Early-Stage Alzheimer’s
Urinary Biomarkers Predict Weaning From Acute Dialysis Therapy
AKI Biomarker Test Assesses Risk of Kidney Damage in Critically Ill Patients
Familial Hypercholesterolemia Patients With ACD Have Elevated Lipoprotein(a)
Circulating Angiogenic Factor Levels Predict Hypertensive Disorders of Pregnancy
Urine Neutrophil Gelatinase-Associated Lipocalin Predicts Acute Kidney Injury
New Blood Cholesterol Testing System Is Cheaper, More Efficient, and Faster
New Analyzer Monitors Blood Ammonium Levels at POC to Facilitate Quick Medical Decisions
Urine Bicarbonate Test Offers Safe Quantification of CFTR Function in Cystic Fibrosis Patients
Cell-Specific Bioorthogonal Tagging of Glycoproteins Developed
AI Combined with Molecule-Making Machine Could Make Complex Chemistry Automated and Accessible
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.